Comparison of Freelite and N-Latex serum free light chain assays: a critical review

Massimo Daves, Andrea Piccin, Vincenzo Roccaforte, Giuseppe Lippi

Original Articles, Volume 31, October, Issue 3

KEYWORDS: free light chain; monoclonal gammopathies; analytical techniques and equipment; comparison; immunoassays

https://doi.org/10.11613/BM.2021.030701

Performance of D-dimer for predicting sepsis mortality in the intensive care unit

Yan-Qiu Han, Li Yan, Lei Zhang, Pei-Heng Ouyang, Peng Li, Giuseppe Lippi, Zhi-De Hu

Original Articles, Volume 31, June, Issue 2

KEYWORDS: sepsis; fibrin/fibrinogen degradation products; intensive care units; treatment outcome; disseminated intravascular coagulation

https://doi.org/10.11613/BM.2021.020709

Defining laboratory medicine: a circle cannot be squared

Giuseppe Lippi, Mario Plebani

Letter to the Editor, Volume 31, June, Issue 2

KEYWORDS: laboratory medicine; testing; definition

https://doi.org/10.11613/BM.2021.020401

Errors within the total laboratory testing process, from test selection to medical decision-making – A review of causes, consequences, surveillance and solutions

Cornelia Mrazek, Giuseppe Lippi, Martin H Keppel, Thomas K Felder, Hannes Oberkofler, Elisabeth Haschke-Becher, Janne Cadamuro

Review, Volume 30, June, Issue 2

KEYWORDS: total testing process; extra-analytical phase; quality indicators; laboratory medicine; patient safety

https://doi.org/10.11613/BM.2020.020502

Study of the preanalytical variables affecting the measurement of clinically relevant free-circulating microRNAs: focus on sample matrix, platelet depletion, and storage conditions

Martina Faraldi, Veronica Sansoni, Silvia Perego, Marta Gomarasca, Jakub Kortas, Ewa Ziemann, Giuseppe Banfi, Giovanni Lombardi

Original Articles, Volume 30, February, Issue 1

KEYWORDS: circulating microRNA; biomarkers; plasma; preanalytical phase

https://doi.org/10.11613/BM.2020.010703

Integrated diagnostics: the future of laboratory medicine?

Giuseppe Lippi, Mario Plebani

Review, Volume 30, February, Issue 1

KEYWORDS: integrated diagnostics; laboratory medicine; pathology; radiology

https://doi.org/10.11613/BM.2020.010501

European survey on preanalytical sample handling – Part 2: Practices of European laboratories on monitoring and processing haemolytic, icteric and lipemic samples. On behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE)

Janne Cadamuro, Giuseppe Lippi, Alexander von Meyer, Mercedes Ibarz, Edmee van Dongen, Michael Cornes, Mads Nybo, Pieter Vermeersch, Kjell Grankvist, Joao Tiago Guimaraes, Gunn B.B. Kristensen, Barbara de la Salle, Ana-Maria Simundic

Original Articles, Volume 29, June, Issue 2

KEYWORDS: preanalytics; standardization; survey

https://doi.org/10.11613/BM.2019.020705

European survey on preanalytical sample handling – Part 1: How do European laboratories monitor the preanalytical phase? On behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE)

Janne Cadamuro, Giuseppe Lippi, Alexander von Meyer, Mercedes Ibarz, Edmee van Dongen, Michael Cornes, Mads Nybo, Pieter Vermeersch, Kjell Grankvist, Joao Tiago Guimaraes, Gunn B.B. Kristensen, Barbara de la Salle, Ana-Maria Simundic

Original Articles, Volume 29, June, Issue 2

KEYWORDS: preanalytics; standardization; survey

https://doi.org/10.11613/BM.2019.020704

A paradigmatic case of haemolysis and pseudohyperkalemia in blood gas analysis

Gian Luca Salvagno, Davide Demonte, Giuseppe Lippi

Preanalytical Mysteries, Volume 29, February, Issue 1

KEYWORDS: potassium; hyperkalemia; preanalytical variability; diagnostic errors

https://doi.org/10.11613/BM.2019.011003

“Ultra-sensitive” cardiac troponins: Requirements for effective implementation in clinical practice

Giuseppe Lippi, Fabian Sanchis-Gomar

Review, Volume 28, October, Issue 3

KEYWORDS: cardiac troponin; myocardial infarction; acute coronary syndrome; diagnostics

https://doi.org/10.11613/BM.2018.030501

Acutely developing, spurious anaemia without actual blood loss. A paradigmatic case report

Giuseppe Lippi, Gianfranco Cervellin

Pre-analytical mysteries, Volume 27, June, Issue 2

KEYWORDS: anaemia; errors; posture; preanalytical variability; case report

https://doi.org/10.11613/BM.2017.045

The alcohol used for cleansing the venipuncture site does not jeopardize blood and plasma alcohol measurement with head-space gas chromatography and an enzymatic assay

Giuseppe Lippi, Ana-Maria Simundic, Giacomo Musile, Elisa Danese, Gianluca Salvagno, Franco Tagliaro

Original papers, Volume 27, June, Issue 2

KEYWORDS: laboratory testing; diagnostics; alcohol; errors; pre-analytical phase

https://doi.org/10.11613/BM.2017.041

Urinary free cortisol assessment by liquid chromatography tandem mass spectrometry: a case study of ion suppression due to unacquainted administration of piperacillin

Elisa Danese, Gian Luca Salvagno, Alessandra Guzzo, Samuele Scurati, Cristiano Fava, Giuseppe Lippi

Pre-analytical Mysteries, Volume 27, October, Issue 3

KEYWORDS: urinary free cortisol; ion suppression; pre-analytical phase; piperacillin; mass spectrometry

https://doi.org/10.11613/BM.2017.031001

Establishing the upper reference limit of Galectin-3 in healthy blood donors

Luisa Agnello, Chiara Bellia, Bruna Lo Sasso, Alessia Pivetti, Maddalena Muratore, Concetta Scazzone, Giulia Bivona, Giuseppe Lippi, Marcello Ciaccio

Original Papers, Volume 27, October, Issue 3

KEYWORDS: galectin-3; blood donors; heart failure; reference values; upper reference limit (URL)

https://doi.org/10.11613/BM.2017.030709

Concerning the vitamin D reference range: pre-analytical and analytical variability of vitamin D measurement

Davide Ferrari, Giovanni Lombardi, Giuseppe Banfi

Review, Volume 27, October, Issue 3

KEYWORDS: vitamin D; biological variability; analytical variability; standardization; DEQAS

https://doi.org/10.11613/BM.2017.030501

Abnormal gel flotation caused by contrast media during adrenal vein sampling

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Matteo Gelati, Antonella Bassi, Alberto Contro, Francesca Pizzolo, Gian Cesare Guidi

Case Report, Volume 26, October, Issue 3

KEYWORDS: preanalytical phase; blood specimen collection; contrast media; gels; phlebotomy

https://doi.org/10.11613/BM.2016.047

The use of S-Monovette is effective to reduce the burden of hemolysis in a large urban emergency department

Giuseppe Lippi, Patrizia Bonelli, Laura Bonfanti, Gianfranco Crevellin

Original papers, Volume 25, February, Issue 1

KEYWORDS: preanalytical phase; hemolysis; blood specimen collection; catheter; emergency department

https://doi.org/10.11613/BM.2015.008

“Real life use” of troponin in the emergency department: a survey of over 3000 cases

Matteo Vidali, Enrica Verzotti, Nicole Cabraz, Francesca Santi, Alessia Puma, Giorgio Bellomo, Alessandro Lupi, Giuseppe Lippi, Gian Carlo Avanzi

Original papers, Volume 25, October, Issue 3

KEYWORDS: troponin I; acute coronary syndrome; emergency service; hospital; chest pain

https://doi.org/10.11613/BM.2015.043

In vitro diagnostic company recalls and medical laboratory practices: an Italian case

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Giorgio Brocco, Gian Cesare Guidi

Case Report, Volume 25, June, Issue 2

KEYWORDS: clinical laboratory techniques; patient safety; laboratory variability; reference standards; quality control; parathyroid hormone

https://doi.org/10.11613/BM.2015.028

Interference of medical contrast media on laboratory testing

Giuseppe Lippi, Massimo Daves, Camilla Mattiuzzi

Review, Volume 24, February, Issue 1

KEYWORDS: errors; analytical interference; contrast media; contrast agents; gadolinium

https://doi.org/10.11613/BM.2014.010

Physical activity - an important preanalytical variable

Fabian Sanchis-Gomar, Giuseppe Lippi

Review, Volume 24, February, Issue 1

KEYWORDS: biomarkers; training; plasma volume; metabolism; cellular damage

https://doi.org/10.11613/BM.2014.009

Contamination of lithium heparin blood by K2-ethylenediaminetetraacetic acid (EDTA): an experimental evaluation

Gabriel Lima-Oliveira, Gian Luca Salvagno, Elisa Danese, Giorgio Brocco, Gian Cesare Guidi, Giuseppe Lippi

Original papers, Volume 24, October, Issue 3

KEYWORDS: contamination; EDTA; patient safety; preanalytical variability; total quality management; preanalytical phase

https://doi.org/10.11613/BM.2014.038

Could light meal jeopardize laboratory coagulation tests?

Gabriel Lima-Oliveira, Gian Luca Salvagno, Giuseppe Lippi, Elisa Danese, Matteo Gelati, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Original papers, Volume 24, October, Issue 3

KEYWORDS: diagnostic errors; fasting; postprandial period; reference values; reproducibility of results.

https://doi.org/10.11613/BM.2014.036

Glycogen phosphorylase isoenzyme BB in the diagnosis of acute myocardial infarction: a meta-analysis

Giuseppe Lippi, Camilla Mattiuzzi, Ivan Comelli, Gianfranco Cervellin

Original papers, Volume 23, February, Issue 1

KEYWORDS: myocardial infarction; ischemic heart disease; glycogen phosphorylase isoenzyme BB; GPBB

https://doi.org/10.11613/BM.2013.010

Evaluation of sample hemolysis in blood collected by S-Monovette® using vacuum or aspiration mode

Giuseppe Lippi, Paola Avanzini, Roberta Musa, Franca Sandei, Rosalia Aloe, Gianfranco Cervellin

Original papers, Volume 23, February, Issue 1

KEYWORDS: hemolysis; hemolyzed specimens; preanalytical variability; blood collection tube; blood drawing

https://doi.org/10.11613/BM.2013.008

The effective reduction of tourniquet application time after minor modification of the CLSI H03-A6 blood collection procedure

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Original papers, Volume 23, October, Issue 3

KEYWORDS: venous stasis; preanalytical phase; tourniquets; phlebotomy; practice guidelines

https://doi.org/10.11613/BM.2013.037

Reduction of gross hemolysis in catheter-drawn blood using Greiner Holdex® tube holder

Giuseppe Lippi, Paola Avanzini, Rosalia Aloe, Gianfranco Cervellin

Original papers, Volume 23, October, Issue 3

KEYWORDS: preanalytical variability; hemolysis; sample quality; intravenous line

https://doi.org/10.11613/BM.2013.036

Incorrect order of draw could be mitigate the patient safety: a phlebotomy management case report

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Case report, Volume 23, June, Issue 2

KEYWORDS: clinical laboratory techniques; preanalytical phase; laboratory variability; blood specimen collection; EDTA contamination carryover

https://doi.org/10.11613/BM.2013.026

Avoidance to wipe alcohol before venipuncture is not a source of spurious hemolysis

Gian Luca Salvagno, Elisa Danese, Gabriel Lima-Oliveira, Gian Cesare Guidi, Giuseppe Lippi

Original papers, Volume 23, June, Issue 2

KEYWORDS: preanalytical variability; hemolysis; alcohol; practice guideline

https://doi.org/10.11613/BM.2013.023

Critical review and meta-analysis of spurious hemolysis in blood samples collected from intravenous catheters

Giuseppe Lippi, Gianfranco Cervellin, Camilla Mattiuzzi

Original papers, Volume 23, June, Issue 2

KEYWORDS: hemolysis; preanalytical variability; catheters; meta-analysis

https://doi.org/10.11613/BM.2013.022

Biomedical research platforms and their influence on article submissions and journal rankings: An update

Giuseppe Lippi, Emmanuel J. Favaloro, Ana-Maria Simundic

Editorial, Volume 22, February, Issue 1

KEYWORDS: impact factor; indexing; Medline

https://doi.org/10.11613/BM.2012.002

Impact of the phlebotomy training based on CLSI/NCCLS H03-A6 – procedures for the collection of diagnostic blood

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Original papers, Volume 22, October, Issue 3

KEYWORDS: phlebotomy; blood specimen collection; tourniquet application time; CLSI documents; pre-analytic variability; extra- analytical variability

https://doi.org/10.11613/BM.2012.036

The new oral anticoagulants and the future of haemostasis laboratory testing

Emmanuel J. Favaloro, Giuseppe Lippi

Review, Volume 22, October, Issue 3

KEYWORDS: haemostasis; coagulation; laboratory tests; anticoagulants; anti-thrombotics; Dabigatran; Rivaroxaban.

https://doi.org/10.11613/BM.2012.035

Cardiac indexes, cardiac damage biomarkers and energy expenditure in professional cyclists during the Giro d’Italia 3-weeks stage race

Roberto Corsetti, Giovanni Lombardi, Alessandra Barassi, Patrizia Lanteri, Alessandra Colombini, Gianvico Melzi D’Eril, Giuseppe Banfi

Original papers, Volume 22, June, Issue 2

KEYWORDS: amino-terminal pro-brain natriuretic peptide; troponin T; physical endurance; energy expenditure

https://doi.org/10.11613/BM.2012.026

Preanalytical management: serum vacuum tubes validation for routine clinical chemistry

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Original papers, Volume 22, June, Issue 2

KEYWORDS: preanalytical variability; blood collection; serum samples; vacuum tubes; validation process

https://doi.org/10.11613/BM.2012.021

Preanalytical phase – a continuous challenge for laboratory professionals

Ana-Maria Simundic, Giuseppe Lippi

Editorial, Volume 22, June, Issue 2

KEYWORDS: preanalytical phase; errors; quality indicators; phlebotomy; blood sampling

https://doi.org/10.11613/BM.2012.017

Non-commutability of results of highly sensitive troponin I and T immunoassays

Giuseppe Lippi, Gianfranco Cervellin, Rosalia Aloe, Martina Montagnana, Gian Luca Salvagno, Gian Cesare Guidi

Short communications, Volume 22, February, Issue 1

KEYWORDS: troponin; biological markers; commutability; myocardial infarction

https://doi.org/10.11613/BM.2012.015

Effects of winter swimming on haematological parameters

Giovanni Lombardi, Christian Ricci, Giuseppe Banfi

Original papers, Volume 21, February, Issue 1

KEYWORDS: winter swimming; cold stress; red blood cells; platelets; leukocytes; haematology

https://doi.org/10.11613/BM.2011.014

Cardiac troponins and physical exercise. It’s time to make a point

Giuseppe Lippi, Gianfranco Cervellin, Giuseppe Banfi, Mario Plebani

Short review, Volume 21, February, Issue 1

KEYWORDS: sports; biomarkers; acute myocardial infarction; cardiac injury; troponin

https://doi.org/10.11613/BM.2011.012

Evaluation of hematocrit bias on blood glucose measurement with six different portable glucose meters

Massimo Daves, Roberto Cemin, Bruno Fattor, Giovanni Cosio, Gian Luca Salvagno, Francesco Rizza, Giuseppe Lippi

Original papers, Volume 21, October, Issue 3

KEYWORDS: portable glucose meters; hematocrit bias; analytic performance

https://doi.org/10.11613/BM.2011.041

Studies on in vitro hemolysis and utility of corrective formulas for reporting results on hemolyzed specimens

Giuseppe Lippi, Paola Avanzini, Fernan da Pavesi, Mirco Bardi, Luigi Ippolito, Rosalia Aloe, Emmanuel J Favaloro

Original papers, Volume 21, October, Issue 3

KEYWORDS: hemolysis; hemolyzed specimens; interference; preanalytical variability

https://doi.org/10.11613/BM.2011.040

Molecular pathways in cancer-related inflammation

Annalisa Del Prete, Paola Allavena, Giuseppe Santoro, Ruggiero Fumarulo, Massimiliano M. Corsi, Alberto Mantovani

Special issue, Volume 21, October, Issue 3

KEYWORDS: cancer-related inflammation; cytokines; chemokines; macrophages

https://doi.org/10.11613/BM.2011.036

New ways to deal with known preanalytical issues: use of transilluminator instead of tourniquet for easing vein access and eliminating stasis on clinical biochemistry

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Cristovão Luis Pitanguiera Manguera, Nairo M. Sumita, Geraldo Picheth, Gian Cesare Guidi, Marileia Scartezini

Original papers, Volume 21, June, Issue 2

KEYWORDS: phlebotomy and blood collection; pre analytical phase; quality management system in clinical laboratory; transillumination; venous stasis.

https://doi.org/10.11613/BM.2011.024

Development of a preanalytical errors recording software

Giuseppe Lippi, Patrizia Bonelli, Rossana Rossi, Mirco Bardi, Rosalia Aloe, Alberta Caleffi, Enrichetta Bonilauri

Original papers, Volume 20, February, Issue 1

KEYWORDS: errors; laboratory testing; computer program; informatics; extra-analytical phase

https://doi.org/10.11613/BM.2010.011

Total quality in laboratory diagnostics. It's time to think outside the box

Giuseppe Lippi, Ana-Maria Simundic

Editorial, Volume 20, February, Issue 1

KEYWORDS: patient safety; laboratory diagnostics; preanalytical phase; errors; quality

https://doi.org/10.11613/BM.2010.001

Quality in the extra-analytical phases of urinalysis

Alberta Caleffi, Fabio Manoni, Maria Grazia Alessio, Cosimo Ottomano, Giuseppe Lippi

Special issue, Volume 20, June, Issue 2

KEYWORDS: urine; urinalysis; quality; prenalytical phase

https://doi.org/10.11613/BM.2010.022

Hemolysis detection and management of hemolyzed specimens

Ana-Maria Simundic, Elizabeta Topic, Nora Nikolac, Giuseppe Lippi

Special issue, Volume 20, June, Issue 2

KEYWORDS: hemolysis; extra-analytical quality; errors; laboratory testing; interference

https://doi.org/10.11613/BM.2010.018

Overview on patient safety in healthcare and laboratory diagnostics

Giuseppe Lippi, Ana-Maria Simundic, Ca­mil­la Mat­tiuz­zi

Special issue, Volume 20, June, Issue 2

KEYWORDS: errors; quality; patient safety; outcome; prevention

https://doi.org/10.11613/BM.2010.015

Quality in laboratory diagnostics: from theory to practice

Giuseppe Lippi, Mario Plebani, Ana-Maria Simundic

Special issue, Volume 20, June, Issue 2

https://doi.org/10.11613/BM.2010.014

Influence of age and gender variations on glomerular filtration rate estimated by the MCQE formula

Giuseppe Lippi, Nicola Tessitore, Martina Montagnana, Valeria Bedogna, Gian Luca Salvagno, Giovanni Targher, Antonio Lupo, Gian Cesare Guidi

Original papers, Volume 19, February, Issue 1

KEYWORDS: creatinine; glomerular filtration rate; kidney function; MDRD; MCQE

https://doi.org/10.11613/BM.2009.008

Serum prolactin in professional soccer players

Giuseppe Lippi, Francesco De Vita, Gian Luca Salvagno, Martina Montagnana, Giovanni Targher, Gian Cesare Guidi

Original papers, Volume 19, June, Issue 2

KEYWORDS: hormones; prolactin; physical exercise; reference range; sports

https://doi.org/10.11613/BM.2009.016

The missing link between genotype, phenotype and clinics

Giuseppe Lippi, Emmanuel J Favaloro

Review, Volume 19, June, Issue 2

KEYWORDS: genotype; phenotype; clinics; genetic testing

https://doi.org/10.11613/BM.2009.013

Relationship between uric acid, hyperglycemia and hypertriglyceridemia in general population

Giuseppe Lippi, Martina Montagnana, Giovanni Targher, Gian Luca Salvagno, Gian Cesare Guidi

Original papers, Volume 18, February, Issue 1

KEYWORDS: diabetes; fasting plasma glucose; hyperglycemia; metabolic syndrome; hypertriglyceridemia; uric acid

https://doi.org/10.11613/BM.2008.005