Laboratory professionals’ attitudes towards ISO 15189:2012 accreditation: an anonymous survey of three Croatian accredited medical laboratories

Ivana Lapić, Dunja Rogić, Matea Ivić, Marina Tomičević, Mirjana Mariana Kardum Paro, Lovorka Đerek, Ines Alpeza Viman

Original Articles, Volume 31, June, Issue 2

KEYWORDS: accreditation; quality assurance; ISO 15189:2012; survey; satisfaction

https://doi.org/10.11613/BM.2021.020712

Reporting categories in urine test strip analysis: Croatian survey and call for action

Ana Dojder, Dora Vuljanić, Valentina Špoljarić, Andrea Saračević, Lora Dukić, Jasna Leniček-Krleža, Jelena Vlašić-Tanasković, Ivana Maradin, Ana Grzunov, Ana-Maria Šimundić

Original Articles, Volume 29, June, Issue 2

KEYWORDS: urine; test strips; reporting; harmonization

https://doi.org/10.11613/BM.2018.020709

Effect of cold agglutinins on red blood cell parameters in a trauma patient: a case report

Anita Topic, Lara Milevoj Kopcinovic, Ana Bronic, Marina Pavic

Preanalytical mysteries, Volume 28, October, Issue 3

KEYWORDS: cold agglutinins; preanalytical errors; red blood cell count; spurious complete blood count results

https://doi.org/10.11613/BM.2018.031001

Biotin and high-sensitivity cardiac troponin T assay

Aurélien Schrapp, François Fraissinet, Charles Hervouet, Hélène Girot, Valéry Brunel

Short Communication, Volume 28, October, Issue 3

KEYWORDS: troponin T; biotin; multiple sclerosis; preanalytical phase

https://doi.org/10.11613/BM.2018.030901

Metabolic follow-up of a Croatian patient with gyrate atrophy and a new mutation in the gene: a case report

Marija Zekušić, Ana Škaričić, Ksenija Fumić, Dunja Rogić, Tamara Žigman, Danijela Petković Ramadža, Nenad Vukojević, Véronique Rüfenacht, Valentina Uroić, Ivo Barić

Case Report, Volume 28, October, Issue 3

KEYWORDS: ornithinemia; amino acids; tandem mass spectrometry

https://doi.org/10.11613/BM.2018.030801

Significance of LDL and HDL subclasses characterization in the assessment of risk for colorectal cancer development

Milica Stevanovic, Jelena Vekic, Natasa Bogavac-Stanojevic, Jelena Janac, Zeljka Stjepanovic, Dejan Zeljkovic, Bratislav Trifunovic, Vesna Spasojevic-Kalimanovska, Aleksandra Zeljkovic

Original Papers, Volume 28, October, Issue 3

KEYWORDS: colorectal cancer; risk prediction; lipoprotein subclasses; lipoprotein size; cost-effectiveness

https://doi.org/10.11613/BM.2018.030713

The diagnostic accuracy of clinical and laboratory parameters in the diagnosis of acute appendicitis in the adult emergency department population - a case control pilot study

Ivo Soldo, Vanja Radisic Biljak, Branko Bakula, Maja Bakula, Ana-Maria Simundic

Original Papers, Volume 28, October, Issue 3

KEYWORDS: appendicitis; emergency service; white blood cell count; C-reactive protein; urinalysis

https://doi.org/10.11613/BM.2018.030712

A collaborative study by the Working Group on Hemostasis and Thrombosis of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC) on the interference of haemolysis on five routine blood coagulation tests by evaluation of 269

Chiara Novelli, Matteo Vidali, Bruno Brando, Benedetto Morelli, Giovanna Andreani, Marina Arini, Paola Calzoni, Roberta Giacomello, Barbara Montaruli, Emanuela Muccini, Angela Papa, Paola Pradella, Lucia Ruocco, Fosca Siviero, Filomena Gemma Viola, Mario

Original Papers, Volume 28, October, Issue 3

KEYWORDS: blood coagulation tests; haemolysis; preanalytical phase

https://doi.org/10.11613/BM.2018.030711

Calcium-stimulated calcitonin - The “new standard” in the diagnosis of thyroid C-cell disease - clinically relevant gender-specific cut-off levels for an “old test”

Martin B. Niederle, Christian Scheuba, Alois Gessl, Shuren Li, Oskar Koperek, Christian Bieglmayer, Philipp Riss, Andreas Selberherr, Bruno Niederle

Original Papers, Volume 28, October, Issue 3

KEYWORDS: medullary thyroid cancer; thyroid; calcitonin; calcium gluconate; pentagastrin

https://doi.org/10.11613/BM.2018.030710

Reducing test request for anti-thyroglobulin and anti-thyroid peroxidase antibodies: trends before and after interventions based on rejection rules and profile management

Pedro Sánchez Pellicer, Ruth González Tamayo, Vicente Navarro López

Original Papers, Volume 28, October, Issue 3

KEYWORDS: demand management laboratory; test laboratory request; anti-thyroid antibodies; anti-thyroid peroxidase antibodies; anti-thyroglobulin antibodies

https://doi.org/10.11613/BM.2018.030709

Evaluation of the analytical performances of the Cobas c513 analyser for HbA1c assay

Stéphane Jaisson, Nathalie Leroy, Michel Soulard, Aurore Desmons, Emmanuelle Guillard, Philippe Gillery

Original Papers, Volume 28, October, Issue 3

KEYWORDS: diabetes; evaluation; HbA; immunoassay

https://doi.org/10.11613/BM.2018.030708

Analysis of selected T cell subsets in peripheral blood after exhaustive effort among elite soccer players

Dorota Kostrzewa-Nowak, Robert Nowak

Original Papers, Volume 28, October, Issue 3

KEYWORDS: athletes; fatigue; flow cytometry; soccer; T-lymphocytes

https://doi.org/10.11613/BM.2018.030707

Computer physician order entry (CPOE) as a strategy to estimate laboratory activity and costs associated with cancer clinical trials

Enrique Rodriguez-Borja, Africa Corchon-Peyrallo, Macarena Diaz-Gimenez, Arturo Carratala-Calvo

Original Papers, Volume 28, October, Issue 3

KEYWORDS: clinical decision support systems; computer physician order entry; health care costs; laboratory management; randomized controlled trials

https://doi.org/10.11613/BM.2018.030706

Effect of sample processing and time delay on cell count and chemistry tests in cerebrospinal fluid collected from drainage systems

Ana Mlinarić, Željka Vogrinc, Zrinka Drenšek

Original Papers, Volume 28, October, Issue 3

KEYWORDS: cerebrospinal fluid; extra-ventricular drainage system; cell count; biochemistry analyses; turnaround time

https://doi.org/10.11613/BM.2018.030705

Haematology specimen acceptability: a national survey in Chinese laboratories

Yuanyuan Ye, Wei Wang, Haijian Zhao, Falin He, Kun Zhong, Shuai Yuan, Yuxuan Du, Bingquan Chen, Zhiguo Wang

Original Papers, Volume 28, October, Issue 3

KEYWORDS: quality indicator; preanalytical phase; quality control; haematology; survey

https://doi.org/10.11613/BM.2018.030704

Detection of annexin A8 antibodies in serum of patients with antiphospholipid syndrome

Philipp Scholz, Markus Auler, Johannes Ruthard, Bent Brachvogel, Andreas R. Klatt, Thomas Streichert

Original Papers, Volume 28, October, Issue 3

KEYWORDS: annexin A8; antiphospholipid syndrome; antiphospholipid antibodies

https://doi.org/10.11613/BM.2018.030703

Association of abdominal aortic aneurysm diameter with insulin resistance index

Fabien Lareyre, Claudine Moratal, Elamine Zereg, Joseph Carboni, Patricia Panaïa-Ferrari, Pascale Bayer, Elixène Jean-Baptiste, Réda Hassen-Khodja, Giulia Chinetti, Juliette Raffort

Original Papers, Volume 28, October, Issue 3

KEYWORDS: diabetes mellitus; abdominal aortic aneurysm; C-peptide; insulin resistance; fructosamine

https://doi.org/10.11613/BM.2018.030702

Improvement of neutrophil gelatinase-associated lipocalin sensitivity and specificity by two plasma measurements in predicting acute kidney injury after cardiac surgery

Giovanni Introcaso, Matteo Nafi, Alice Bonomi, Camilla L’Acqua, Luca Salvi, Roberto Ceriani, Davide Carcione, Annalisa Cattaneo, Maria Teresa Sandri

Original Papers, Volume 28, October, Issue 3

KEYWORDS: neutrophil gelatinase-associated lipocalin; acute kidney injury; cardiovascular surgery; diagnostic accuracy; AKI biomarkers

https://doi.org/10.11613/BM.2018.030701

Red blood cell distribution width in pregnancy: a systematic review

Panagiotis Paliogiannis, Angelo Zinellu, Arduino A. Mangoni, Giampiero Capobianco, Salvatore Dessole, Pier Luigi Cherchi, Ciriaco Carru

Review, Volume 28, October, Issue 3

KEYWORDS: anisocytosis; RDW; pregnancy; preeclampsia; gestational diabetes

https://doi.org/10.11613/BM.2018.030502

“Ultra-sensitive” cardiac troponins: Requirements for effective implementation in clinical practice

Giuseppe Lippi, Fabian Sanchis-Gomar

Review, Volume 28, October, Issue 3

KEYWORDS: cardiac troponin; myocardial infarction; acute coronary syndrome; diagnostics

https://doi.org/10.11613/BM.2018.030501

Informed consent and ethics committee approval in laboratory medicine

Ana Borovecki, Ana Mlinaric, Martina Horvat, Vesna Supak Smolcic

Research Integrity Corner, Volume 28, October, Issue 3

KEYWORDS: informed consent; ethical approval; research; laboratory medicine; ethics committees

https://doi.org/10.11613/BM.2018.030201

Corrigendum to: The potential of component-resolved diagnosis in laboratory diagnostics of allergy

Slavica Dodig, Ivana Čepelak

Corrigendum, Volume 28, June, Issue 2

https://doi.org/10.11613/BM.2018.021201

Evaluating analytical quality in clinical biochemistry laboratory using Six Sigma

Xuehui Mao, Jing Shao, Bingchang Zhang, Yong Wang

Short Communications: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: Sigma metrics; total allowable error; quality control; bias

https://doi.org/10.11613/BM.2018.020904

Using Sigma metrics to establish analytical product performance requirements and optimize analytical performance of an diagnostic assay using a theoretical total PSA assay as an example

Victoria Petrides, Sharon Schneider

Short Communications: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: total quality management; decision making; goals

https://doi.org/10.11613/BM.2018.020903

Comparison of Barricor™ vs. lithium heparin tubes for selected routine biochemical analytes and evaluation of post centrifugation stability

Anne Marie Dupuy, Stéphanie Badiou, Delphine Daubin, Anne Sophie Bargnoux, Chloé Magnan, Kadda Klouche, Jean Paul Cristol

Short Communications, Volume 28, June, Issue 2

KEYWORDS: blood specimen collection; plasma; test tube; evaluation

https://doi.org/10.11613/BM.2018.020902

Storage stability of commonly used haematological parameters at 33 °C

Ashish Jain, Sanchit Jain, Neha Singh, Priyanka Aswal, Shweta Pal, Sushant Kumar Meinia, Nilotpal Chowdhury

Short Communications, Volume 28, June, Issue 2

KEYWORDS: pre-analytical error; erythrocyte indices; laboratory errors; platelet count; sample stability

https://doi.org/10.11613/BM.2018.020901

Utilization of a healthcare failure mode and effects analysis to identify error sources in the preanalytical phase in two tertiary hospital laboratories

Adolfo Romero, Juan Gómez-Salgado, Adolfo Romero-Arana, Carlos Ruiz-Frutos

Original Papers, Volume 28, June, Issue 2

KEYWORDS: preanalytical phase; Healthcare Failure Mode and Effects Analysis; quality assessment; errors

https://doi.org/10.11613/BM.2018.020713

Evaluation of the analytical performances of Cobas 6500 and Sysmex UN series automated urinalysis systems with manual microscopic particle counting

Ebubekir Bakan, Zafer Bayraktutan, Nurcan Kilic Baygutalp, Mehmet Ali Gul, Fatma Zuhal Umudum, Nuri Bakan

Original Papers, Volume 28, June, Issue 2

KEYWORDS: urinalysis; automated urinalysis; manual microscopy

https://doi.org/10.11613/BM.2018.020712

Comparison between Sigma metrics in four accredited Egyptian medical laboratories in some biochemical tests: an initiative towards sigma calculation harmonization

Rania El Sharkawy, Sten Westgard, Ahmed M Awad, AbdelKarem Omneya I Ahmed, El Hadidi Iman, Ahmed Gaballah, Eman Shaheen

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: sigma; bias; coefficient of variation; harmonization; total allowable error

https://doi.org/10.11613/BM.2018.020711

Comprehensive evaluation of the internal and external quality control to redefine analytical quality goals

Beatriz Varela, Gonzalo Pacheco

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: total quality management; quality control; bias; laboratory proficiency testing/methods; clinical chemistry test

https://doi.org/10.11613/BM.2018.020710

Application of Sigma metrics in assessing the clinical performance of verified versus non-verified reagents for routine biochemical analytes

Shuang Cao, Xiaosong Qin

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: quality assessment; Sigma metrics; method decision chart; total allowable error

https://doi.org/10.11613/BM.2018.020709

Sigma metrics for assessing the analytical quality of clinical chemistry assays: a comparison of two approaches

Xiuzhi Guo, Tianjiao Zhang, Xuehui Gao, Pengchang Li, Tingting You, Qiong Wu, Jie Wu, Fang Zhao, Liangyu Xia, Ermu Xu, Ling Qiu, Xinqi Cheng

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: Six Sigma; proficiency testing; internal quality control; allowable total error

https://doi.org/10.11613/BM.2018.020708

Risk analysis and assessment based on Sigma metrics and intended use

Yong Xia, Hao Xue, Cunliang Yan, Bowen Li, ShuQiong Zhang, Mingyang Li, Ling Ji

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: risk analysis; risk assessment; Six Sigma; Sigma metrics; failure mode and effects analysis

https://doi.org/10.11613/BM.2018.020707

Assessing performance in pre-season wrestling athletes using biomarkers

Ionas Papassotiriou, Artemissia-Phoebe Nifli

Original Papers, Volume 28, June, Issue 2

KEYWORDS: exercise; glucose; lactic acid; creatinine; body composition

https://doi.org/10.11613/BM.2018.020706

Verification of a novel point-of-care HbA device in real world clinical practice by comparison to three high performance liquid chromatography instruments

Yufei Wang, Wei Peng, Junling Tang, Lu Dong, Chengchen Gu, Xin Zhang, Jian Zhou, Weiping Jia

Original Papers, Volume 28, June, Issue 2

KEYWORDS: point-of-care testing; glycated haemoglobin A1c; diabetes mellitus; evaluation studies

https://doi.org/10.11613/BM.2018.020705

The impact of delayed sample handling and type of anticoagulant on the interpretation of dysplastic signs detected by flow cytometry

Bettina Kárai, Zsófia Miltényi, Lajos Gergely, Marianna Száraz-Széles, János Kappelmayer, Zsuzsanna Hevessy

Original Papers, Volume 28, June, Issue 2

KEYWORDS: myelodysplastic syndromes; flow cytometry; pre-analytical error

https://doi.org/10.11613/BM.2018.020704

Maturity onset diabetes of the young due to variants in Croatia

Tamara Pavić, Agata Juszczak, Edita Pape Medvidović, Carla Burrows, Mario Šekerija, Amanda J Bennett, Jadranka Ćuća Knežević, Anna L Gloyn, Gordan Lauc, Mark I McCarthy, Olga Gornik, Katharine R Owen

Original Papers, Volume 28, June, Issue 2

KEYWORDS: ; maturity onset diabetes of the young (MODY); monogenic diabetes; prevalence study

https://doi.org/10.11613/BM.2018.020703

National survey on internal quality control for tumour markers in clinical laboratories in China

Wei Wang, Kun Zhong, Shuai Yuan, Falin He, Yuxuan Du, Zhehui Hu, Zhiguo Wang

Original Papers, Volume 28, June, Issue 2

KEYWORDS: internal quality control; tumour marker; imprecision; biological variation

https://doi.org/10.11613/BM.2018.020702

Effect of different pre-analytical conditions on plasma lactate concentration

Ivana Rako, Ana Mlinaric, Monika Dozelencic, Gordana Fressl Juros, Dunja Rogic

Original Papers, Volume 28, June, Issue 2

KEYWORDS: plasma lactate; blood analysis; blood specimen collection; haemolysis; pre-analytical phase

https://doi.org/10.11613/BM.2018.020701

Sigma metrics in laboratory medicine revisited: We are on the right road with the wrong map

Wytze P. Oosterhuis, Abdurrahman Coskun

Review: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: biological variation; Six Sigma; Sigma metrics; total error; number of distinct categories

https://doi.org/10.11613/BM.2018.020503

Analytical Sigma metrics: A review of Six Sigma implementation tools for medical laboratories

Sten Westgard, Hassan Bayat, James O Westgard

Review: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: Six Sigma metrics; quality control frequency; OPSpecs chart; method decision chart; Westgard rules

https://doi.org/10.11613/BM.2018.020502

The potential of component-resolved diagnosis in laboratory diagnostics of allergy

Slavica Dodig, Ivana Čepelak

Review, Volume 28, June, Issue 2

KEYWORDS: allergy; IgE; component-resolved diagnosis

https://doi.org/10.11613/BM.2018.020501

Special issue on Six Sigma metrics - experiences and recommendations

Sten Westgard, Hassan Bayat, James O Westgard

Editorial: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: Six Sigma; Sigma metrics; quality control

https://doi.org/10.11613/BM.2018.020301

Expected long-term defect rate of analytical performance in the medical laboratory: Assured Sigma versus observed Sigma

Hassan Bayat

Lessons in Biostatistics: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: medical laboratory; Sigma metrics; Six Sigma; allowable total error

https://doi.org/10.11613/BM.2018.020101

Corrigendum to: Nurses’ knowledge on phlebotomy in tertiary hospitals in China: a cross-sectional multicentric survey

Qian Cai, Yunxian Zhou, Dagan Yang

Corrigendum, Volume 28, February, Issue 1

https://doi.org/10.11613/BM.2018.011202

Corrigendum to: Minimum requirements for the estimation of the measurement uncertainty: Recommendations of the joint Working group for uncertainty of measurement of the CSMBLM and CCMB

Ivana Ćelap, Ines Vukasović, Gordana Juričić, Ana-Maria Šimundić

Corrigendum, Volume 28, February, Issue 1

https://doi.org/10.11613/BM.2018.011201

Pseudohyperkalemia - Potassium released from cells due to clotting and centrifugation - a case report

Tomáš Šálek

Pre-analytical Mysteries, Volume 28, February, Issue 1

KEYWORDS: hyperkalemia; case report; electrolytes; pseudohyperkalemia

https://doi.org/10.11613/BM.2018.011002

Elevated zinc concentrations in a 5 months old infant: A case report

Eva Rabing Brix Petersen, Sven Mortensen, Mads Nybo

Pre-analytical Mysteries, Volume 28, February, Issue 1

KEYWORDS: capillary blood sample; case report; pre-analytical phase; zinc

https://doi.org/10.11613/BM.2018.011001

Neutrophil gelatinase-associated lipocalin and acute kidney injury in endovascular aneurysm repair or open aortic repair: a pilot study

Benedetta Rampoldi, Serena Tessarolo, Paola Giubbilini, Paola Gaia, Samantha D. Corino, Sarah Mazza, Roberta Rigolini, Marco Dei Poli, Elena Vianello, Massimiliano M. Corsi Romanelli, Elena Costa

Short Communications, Volume 28, February, Issue 1

KEYWORDS: acute kidney injury; neutrophil gelatinase-associated lipocalin; cardiovascular surgery; early detection; urinary biomarkers

https://doi.org/10.11613/BM.2018.010904

Upfront dilution of ferritin samples to reduce hook effect, improve turnaround time and reduce costs

Shu Juan Wu, Joshua A. Hayden

Short Communications, Volume 28, February, Issue 1

KEYWORDS: immunoassay; prozone effect; ferritin; turnaround time

https://doi.org/10.11613/BM.2018.010903

Reference intervals for six salivary cortisol measures based on the Croatian Late Adolescence Stress Study (CLASS)

Daniela Šupe-Domić, Goran Milas, Lada Stanišić, Irena Drmić Hofman, Irena Martinović Klarić

Short Communications, Volume 28, February, Issue 1

KEYWORDS: salivary cortisol; reference intervals; late adolescence

https://doi.org/10.11613/BM.2018.010902

Appropriateness of digoxin measurement in hospitalized patients

Seyma Oncu, Ayse Gelal, Ozgur Aslan, Reyhan S Ucku

Short Communications, Volume 28, February, Issue 1

KEYWORDS: digoxin; therapeutic drug monitoring; heart failure; electronic health records

https://doi.org/10.11613/BM.2018.010901

Gamma heavy-chain disease accompanied with follicular lymphoma: a case report

Paula San-José, Vicente Aguadero, Granada Perea, Meritxell Estrada, Eugenio Berlanga

Case Reports, Volume 28, February, Issue 1

KEYWORDS: paraproteins; electrophoresis; lymphoma; heavy chain disease

https://doi.org/10.11613/BM.2018.010802

Henoch-Schönlein purpura in the third trimester of pregnancy

Ivka Djakovic, Drazan Butorac, Zeljko Vucicevic, Vesna Kosec, Andrea Tesija Kuna, Liborija Lugović-Mihić

Case Reports, Volume 28, February, Issue 1

KEYWORDS: Henoch-Schönlein purpura; leukocytoclastic vasculitis; pregnancy; glomerulonephritis; preeclampsia

https://doi.org/10.11613/BM.2018.010801

Reference interval for immature platelet fraction on Sysmex XN haematology analyser in adult population

Claudia E. Imperiali, Ariadna Arbiol-Roca, Lourdes Sanchez-Navarro, Macarena Dastis-Arias, Juan C. Lopez-Delgado, Anna Cortes-Bosch, Ana Sancho-Cerro, Dolors Dot-Bach

Original Papers, Volume 28, February, Issue 1

KEYWORDS: platelets; haematology; reference values; immature platelet fraction

https://doi.org/10.11613/BM.2018.010708

Preanalytics of urine sediment examination: effect of relative centrifugal force, tube type, volume of sample and supernatant removal

Amalija Bunjevac, Nora Nikolac Gabaj, Marijana Miler, Anita Horvat

Original Papers, Volume 28, February, Issue 1

KEYWORDS: preanalytical phase; laboratory error; urinalysis; urine sediment

https://doi.org/10.11613/BM.2018.010707

Diagnostic value of tumour markers in pleural effusions

Darian Volarić, Veljko Flego, Gordana Žauhar, Ljiljana Bulat-Kardum

Original Papers, Volume 28, February, Issue 1

KEYWORDS: pleural effusion; CA-125 antigen; carcinoembryonic antigen; neuron-specific enolase; cytokeratin 19 fragment

https://doi.org/10.11613/BM.2018.010706

Missed detection of significant positive and negative shifts in gentamicin assay: implications for routine laboratory quality practices

Gus Koerbin, Jiakai Liu, Alex Eigenstetter, Chin Hon Tan, Tony Badrick, Tze Ping Loh

Original Papers, Volume 28, February, Issue 1

KEYWORDS: error; moving average; bias; quality control; quality assurance

https://doi.org/10.11613/BM.2018.010705

Influence of centrifugation conditions on the results of 77 routine clinical chemistry analytes using standard vacuum blood collection tubes and the new BD-Barricor tubes

Janne Cadamuro, Cornelia Mrazek, Alexander B. Leichtle, Ulrike Kipman, Thomas K. Felder, Helmut Wiedemann, Hannes Oberkofler, Georg M. Fiedler, Elisabeth Haschke-Becher

Original Papers, Volume 28, February, Issue 1

KEYWORDS: pre-analytics; centrifugation; diagnostic tests; routine

https://doi.org/10.11613/BM.2018.010704

Nurses’ knowledge on phlebotomy in tertiary hospitals in China: a cross-sectional multicentric survey

Qian Cai, Yunxian Zhou, Dangan Yang

Original Papers, Volume 28, February, Issue 1

KEYWORDS: pre-analytical phase; venous blood sampling; knowledge; nurses; phlebotomy

https://doi.org/10.11613/BM.2018.010703

Fasting conditions: Influence of water intake on clinical chemistry analytes

Silvia F. Benozzi, Gisela Unger, Amparo Campion, Graciela L. Pennacchiotti

Original Papers, Volume 28, February, Issue 1

KEYWORDS: fasting; water intake; blood sample collection; preanalytical variability; clinical chemistry tests

https://doi.org/10.11613/BM.2018.010702

Reliability of CKD-EPI predictive equation in estimating chronic kidney disease prevalence in the Croatian endemic nephropathy area

Mirjana Fuček, Živka Dika, Sandra Karanović, Ivana Vuković Brinar, Vedran Premužić, Jelena Kos, Ante Cvitković, Maja Mišić, Josip Samardžić, Dunja Rogić, Bojan Jelaković

Original Papers, Volume 28, February, Issue 1

KEYWORDS: chronic kidney disease; estimated glomerular filtration rate; predictive equation; endemic nephropathy

https://doi.org/10.11613/BM.2018.010701

Biochemia Medica appoints new Editor-in-Chief and new Senior Editor

Daria Pašalić

Editorial, Volume 28, February, Issue 1

KEYWORDS: editor; journal; scientific writing; publication

https://doi.org/10.11613/BM.2018.010301

Setting the IMPACT (IMProve Access to Clinical Trial data) Observatory baseline

Mersiha Mahmić-Kaknjo, Josip Šimić, Karmela Krleža-Jerić

Research Integrity Corner, Volume 28, February, Issue 1

KEYWORDS: clinical trial data sharing; baseline; databases; registries; Cochrane; scandals

https://doi.org/10.11613/BM.2018.010201

Bayes’ theorem, the ROC diagram and reference values: Definition and use in clinical diagnosis

Anders Kallner

Lessons in Biostatistics, Volume 28, February, Issue 1

KEYWORDS: likelihood ratio; cumulative data analysis; odds; sensitivity; specificity

https://doi.org/10.11613/BM.2018.010101

Biochemia Medica introduces new section: Pre-analytical mysteries

Ana-Maria Simundic, Janne Cadamuro, Michael Cornes

Pre-analytical mysteries, Volume 27, June, Issue 2

https://doi.org/10.11613/BM.2017.044

External quality assessment of medical laboratories in Croatia: preliminary evaluation of post-analytical laboratory testing

Jasna Lenicek Krleza, Adrijana Dorotic, Ana Grzunov

Special Issue: External Quality Assessment in Laboratory Medicine - Original Papers, Volume 27, February, Issue 1

KEYWORDS: post-analytical phase; standardization; external quality assessment; questionnaire

https://doi.org/10.11613/BM.2017.018

Blood gas testing and related measurements: National recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Lora Dukić, Lara Milevoj Kopčinović, Adrijana Dorotić, Ivana Baršić

Review, Volume 26, October, Issue 3

KEYWORDS: blood gas analysis; error; guideline; standardization

https://doi.org/10.11613/BM.2016.036

What’s in a name? The problem of authors’ names in research articles

Ana Marušić

Research integrity corner, Volume 26, June, Issue 2

KEYWORDS: authors names; research authorship; indexing

https://doi.org/10.11613/BM.2016.018

Clinical and diagnostic utility of saliva as a non-invasive diagnostic fluid:
a systematic review

Lazaro Alessandro Soares Nunes, Sayeeda Mussavira, Omana Sukumaran Bindhu

Review Article, Volume 25, June, Issue 2

KEYWORDS: saliva; non-invasive; biological markers; drug monitoring; oral health

https://doi.org/10.11613/BM.2015.018

Abnormal gel flotation in a patient with apperant pneumonia diagnosis: a case report

Fethullah Gerin, Dilber Coban Ramazan, Ozgur Baykan, Onder Sirikci, Goncagul Haklar

Case report, Volume 24, February, Issue 1

KEYWORDS: separator gel; preanalytical phase; blood collection tube; floating gel; hyperproteinemia

https://doi.org/10.11613/BM.2014.021

A deep vein thrombosis caused by 20209C>T mutation in homozygosis of the prothrombin gene in a Caucasian patient

Silvia Izquierdo Álvarez, Eva Barrio Ollero, Francisco Miguel Llinares Sanjuan, Fabiola Lorente Martínez, María Teresa Calvo Martín

Case report, Volume 24, February, Issue 1

KEYWORDS: thrombosis; prothrombin; deep vein thrombosis; 20209C>T mutation homozygosis

https://doi.org/10.11613/BM.2014.018

The importance of having a flexible scope ISO 15189 accreditation and quality specifications based on biological variation – the case of validation of the biochemistry analyzer Dimension Vista

Pilar Fernandez-Calle, Sandra Pelaz, Paloma Oliver, Maria Jose Alcaide, Ruben Gomez-Rioja, Antonio Buno, Jose Manuel Iturzaeta

Original papers, Volume 23, February, Issue 1

KEYWORDS: biological variation; ISO 15189; interchangeability of results; Dimension Vista

https://doi.org/10.11613/BM.2013.011

Incorrect order of draw could be mitigate the patient safety: a phlebotomy management case report

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Case report, Volume 23, June, Issue 2

KEYWORDS: clinical laboratory techniques; preanalytical phase; laboratory variability; blood specimen collection; EDTA contamination carryover

https://doi.org/10.11613/BM.2013.026

The Chi-square test of independence

Mary L. McHugh

Lessons in biostatistics, Volume 23, June, Issue 2

KEYWORDS: Chi-square; non-parametric; assumptions; categorical data; statistical analysis

https://doi.org/10.11613/BM.2013.018

Validation of a laboratory and hospital information system in a medical laboratory accredited according to ISO 15189

Vanja Radisic Biljak, Ivan Ozvald, Andrea Radeljak, Kresimir Majdenic, Branka Lasic, Zoran Siftar, Marijana Vucic Lovrencic, Zlata Flegar-Mestric

Original papers, Volume 22, February, Issue 1

KEYWORDS: accreditation; medical informatics; data transfer; laboratory information system; hospital information system; validation

https://doi.org/10.11613/BM.2012.009

The most common nonconformities encountered during the assessments of medical laboratories in Hong Kong using ISO 15189 as accreditation criteria

Bella Ho, Eric Ho

Original papers, Volume 22, June, Issue 2

KEYWORDS: accreditation; quality improvement; healthcare quality assurance; clinical pathology

https://doi.org/10.11613/BM.2012.027

The effects of different syringe volume, needle size and sample volume on blood gas analysis in syringes washed with heparin

Tuncay Küme, Ali Rıza Şişman, Ahmet Solak, Birsen Tuğlu, Burcu Çinkooğlu, Canan Çoker

Original papers, Volume 22, June, Issue 2

KEYWORDS: blood gas analysis; blood specimen collection; heparin; needles; syringes.

https://doi.org/10.11613/BM.2012.022

Preanalytical management: serum vacuum tubes validation for routine clinical chemistry

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Original papers, Volume 22, June, Issue 2

KEYWORDS: preanalytical variability; blood collection; serum samples; vacuum tubes; validation process

https://doi.org/10.11613/BM.2012.021

Analysis of censored data

Marko Lucijanic, Mladen Petrovecki

Lessons in biostatistics, Volume 22, June, Issue 2

KEYWORDS: actuarial method; censored data; Kaplan-Meier method; Log-rank test; survival analysis

https://doi.org/10.11613/BM.2012.018

Validation of methods performance for routine biochemistry analytes at Cobas 6000 analyzer series module c501

Vesna Supak Smolcic, Lidija Bilic-Zulle, Elizabeta Fisic

Original papers, Volume 21, June, Issue 2

KEYWORDS: validation study; chemistry techniques; analytical; Cobas 6000 analyzer; total error; Passing and Bablock regression

https://doi.org/10.11613/BM.2011.028

Summarizing and presenting numerical data

Vanja Pupovac, Mladen Petrovečki

Lessons in biostatistics, Volume 21, June, Issue 2

KEYWORDS: data; numerical; data presentation; summarizing data

https://doi.org/10.11613/BM.2011.018

Accreditation in clinical laboratories

Tomáš Zima

Special issue, Volume 20, June, Issue 2

KEYWORDS: accreditation; ISO 15189 standard; quality system

https://doi.org/10.11613/BM.2010.026

Quality in coagulation and haemostasis testing

Roslyn Bonar, Emmanuel J. Favaloro, Dorothy M. Adcock

Special issue, Volume 20, June, Issue 2

KEYWORDS: quality; haemostasis; coagulation; internal quality control; external quality assurance

https://doi.org/10.11613/BM.2010.023

Hemolysis detection and management of hemolyzed specimens

Ana-Maria Simundic, Elizabeta Topic, Nora Nikolac, Giuseppe Lippi

Special issue, Volume 20, June, Issue 2

KEYWORDS: hemolysis; extra-analytical quality; errors; laboratory testing; interference

https://doi.org/10.11613/BM.2010.018

A model for results comparison on two different biochemistry analyzers in laboratory accredited according to the ISO 15189

Marijana Miler, Ana-Maria Simundic, Mario Štefanović, Dragica Ferenec-Ružić, Marina Kvaternik, Elizabeta Topić, Nada Vrkić

Original papers, Volume 19, October, Issue 3

KEYWORDS: accreditation; analyzer comparison; internal quality control; laboratory error

https://doi.org/10.11613/BM.2009.027

Analytical performance of the Gem® PremierTM 4000 – a comparison study

Snježana Hrabrić Vlah, Štefica Dvornik, Dino Grdović

Original papers, Volume 19, June, Issue 2

KEYWORDS: point of care testing; Gem® PremierTM 4000; hemoglobin

https://doi.org/10.11613/BM.2009.018

Maternal and cord blood malondialdehyde and antioxidant vitamin levels in normal and preeclamptic women

Mohd Suhail, Mohd Faizul-Suhail

Original papers, Volume 19, June, Issue 2

KEYWORDS: maternal plasma; cord plasma; malondialdehyde; anti-oxidant vitamins; pregnancy; preeclampsia

https://doi.org/10.11613/BM.2009.017

List of reviewers

Index of authors and list of reviewers, Volume 18, October, Issue 3

Abstracts of the 19th Symposyum Croatian Society of Medical Biochemists

Symposium abstracts, Volume 18, June, Issue 2

Index of authors

Index of authors and list of reviewers, Volume 18, October, Issue 3

Hepatotoxicity of antituberculosis drugs in a mother and a child affected by pulmonary tuberculosis - A case report

Slavica Dodig, Miljenko Raos, Ivka Zoričić-Letoja

Case report, Volume 18, February, Issue 1

KEYWORDS: antituberculosis drugs; hepatotoxicity; tuberculosis; child

https://doi.org/10.11613/BM.2008.011

Comparative analysis of multiplex AtheNA Multi-Lyte ANA test system and conventional laboratory methods to detect autoantibodies

Ilza Salamunić, Branka Pauković Sekulić, Adela Galetović, Leida Tandara, Dušanka Martinović Kaliterna

Original papers, Volume 18, February, Issue 1

KEYWORDS: antinuclear antibodies; AtheNA Multi-Lyte ANA test system; ELISA; autoimmune diseases

https://doi.org/10.11613/BM.2008.010

Comparability of Pathromtin SL, Dade Actin FS i STA Cephascreen reagents for activated partial thromboplastin time measurement

Lovorka Đerek, Marcela Živković, Dragica Hašperger, Jasna Juriček, Željko Romić

Original papers, Volume 18, February, Issue 1

KEYWORDS: activated partial thromboplastin time; coagulation analyzers; method comparison

https://doi.org/10.11613/BM.2008.009

Standard error: meaning and interpretation

Mary L. McHugh

Lessons in biostatistics, Volume 18, February, Issue 1

KEYWORDS: statistics; standard error

https://doi.org/10.11613/BM.2008.002

Quantitative in situ hybridization with enhanced sensitivity in soft, bone and tooth tissue using digoxigenin tagged RNA probes

Jelica Gluhak-Heinrich, Wuchen Yang, Marie A. Harris, Stephen E. Harris

Original papers, Volume 18, February, Issue 1

KEYWORDS: quantitative in situ hybridization; digoxigenin probes; paraffin embedded bone tissue

https://doi.org/10.11613/BM.2008.008

C-reactive protein and complement components C3 and C4 in children with latent tuberculosis infection

Slavica Dodig, Daniela Galez, Ivka Zoričić-Letoja, Branka Kristić-Kirin, Kornelija Kovač, Boro Nogalo, Jadranka Živčić, Renata Zrinski-Topić

Original papers, Volume 18, February, Issue 1

KEYWORDS: child; complement C3; complement C4; C-reactive protein; latent tuberculosis infection; tuberculosis

https://doi.org/10.11613/BM.2008.007

Impact factor and evaluation of scientific papers or teams

Tomáš Zima

Editorial, Volume 18, February, Issue 1

https://doi.org/10.11613/BM.2008.001

Biomarkers of enzymatic and non-enzymatic antioxidative defense in type 2 diabetes mellitus – comparative analysis

Emina Čolak, Vesna Dimitrijević-Srećković, Predrag B. Djordjević, Sanja Stanković, Biljana Glišić, Branko Srećković, Nada Majkić-Singh

Original papers, Volume 18, February, Issue 1

KEYWORDS: oxidative stress; antioxidant defense; type 2 diabetes mellitus; cardiovascular complications; comparative analysis

https://doi.org/10.11613/BM.2008.006

Book review: Tietz Fundamentals of Clinical Chemistry

Dunja Rogić

Opinion, Volume 18, October, Issue 3

Relationship between uric acid, hyperglycemia and hypertriglyceridemia in general population

Giuseppe Lippi, Martina Montagnana, Giovanni Targher, Gian Luca Salvagno, Gian Cesare Guidi

Original papers, Volume 18, February, Issue 1

KEYWORDS: diabetes; fasting plasma glucose; hyperglycemia; metabolic syndrome; hypertriglyceridemia; uric acid

https://doi.org/10.11613/BM.2008.005

Latent tuberculosis infection in a subject with diabetes mellitus – a case report

Slavica Dodig, Renata Zrinski Topić, Jadranka Živčić

Case report, Volume 18, October, Issue 3

KEYWORDS: Latent tuberculosis infection; diabetes mellitus; diabetes mellitus type 1; IFN-gamma

https://doi.org/10.11613/BM.2008.033

Accu Chek Compact Plus blood glucometer evaluation

Jelena Kozar, Ana-Maria Simundic, Nora Nikolac, Marijana Žirović, Elizabeta Topić

Original papers, Volume 18, October, Issue 3

KEYWORDS: accuracy; precision; analytical evaluation; self monitoring blood glucose device; Bland-Altman; Clarke Error Grid analysis

https://doi.org/10.11613/BM.2008.032

Evaluation of the Primus Ultra2 HPLC system for HbA2 measurement and β-thalassemia screening

Eloísa Urrechaga

Original papers, Volume 18, October, Issue 3

KEYWORDS: HbA2 analysis; β-thalassemia screening; HPLC

https://doi.org/10.11613/BM.2008.031

Association between Pro12Ala and His477His polymorphisms in PPARG gene and insulin resistance in patients with polycystic ovary syndrome

Jana Dragojevič, Janja Marc, Barbara Mlinar

Original papers, Volume 18, October, Issue 3

KEYWORDS: PPARγ; polymorphism; insulin resistance; PCOS; hsCRP

https://doi.org/10.11613/BM.2008.030

Alterations in antioxidant and pro-oxidant balance in preeclampsia – impact on erythrocyte osmotic fragility

Mohd Suhail, Mohd Faizul Suhail, Hina Khan

Original papers, Volume 18, October, Issue 3

KEYWORDS: preeclampsia; nonenzymatic antioxidants and oxidants; enzymatic antioxidants; erythrocyte osmotic fragility

https://doi.org/10.11613/BM.2008.029

Body mass index in patients with positive or suspected coronary artery disease: a large Croatian cohort

Daria Pašalić, Goran Ferenčak, Branka Gršković, Ana Stavljenić-Rukavina

Original papers, Volume 18, October, Issue 3

KEYWORDS: body mass index; coronary artery disease; risk factors

https://doi.org/10.11613/BM.2008.028

Quality indicators

Ana-Maria Simundic, Elizabeta Topić

Short review, Volume 18, October, Issue 3

KEYWORDS: quality indicators; Total Quality Management; benchmarking; continuous improvement; accreditation; quality

https://doi.org/10.11613/BM.2008.027

Apoptosis – the potential pathophysiological mechanism in mood disorders modifiable by lithium salts

Dalibor Karlović

Review, Volume 18, October, Issue 3

KEYWORDS: lithium salts; mood disorders; apoptosis; mood stabilizers

https://doi.org/10.11613/BM.2008.026

Power analysis in research

Mary L. McHugh

Lessons in biostatistics, Volume 18, October, Issue 3

KEYWORDS: power; significance; effect size; sample size; statistical power

https://doi.org/10.11613/BM.2008.024

Microalbuminuria and risk of cardiovascular diseases in patients with diabetes and hypertension

Joanna Pollak, Grazyna Sypniewska

Review, Volume 18, February, Issue 1

KEYWORDS: microalbuminuria; endothelial dysfunction; cardiovascular risk; diabetes; hypertension

https://doi.org/10.11613/BM.2008.004

A new case of transient hyperphosphatasemia in a 21-month-old child with recurrent wheezing – case report

Renata Zrinski-Topić, Miljenko Raos, Jadranka Demirović, Jadranka Živčić, Ivana Čepelak, Rajka Petrinović, Slavica Dodig

Case report, Volume 18, June, Issue 2

KEYWORDS: hyperphosphatasemia; alkaline phosphatase; isoenzymes; wheezing; infant

https://doi.org/10.11613/BM.2008.023

Determination of D-dimer by different quantitative assays – A harmonization exercise

Mojca Stegnar, Mojca Božič

Original papers, Volume 18, June, Issue 2

KEYWORDS: D-dimer; harmonization; validation

https://doi.org/10.11613/BM.2008.022

Flow cytometric differentiation of the origin of hematuria using fluorescent antiglycophorin antibody

Marija Miloš, Gordana Boršo, Dubravka Čvorišćec

Original papers, Volume 18, June, Issue 2

KEYWORDS: glomerular hematuria; non-glomerular hematuria; flow cytometry

https://doi.org/10.11613/BM.2008.021

The Role of IL-2 and rheumatoid factor in recurrent spontaneous abortion

Hossein Hadinedoushan, Abbas Aflatounian, Morteza Anvari

Original papers, Volume 18, June, Issue 2

KEYWORDS: IL-2; rheumatoid factor; recurrent spontaneous abortion

https://doi.org/10.11613/BM.2008.020

Cellular immune response in Dupuytren’s disease

Márk Plander, Antal Salamon, Erzsébet Toldy, Gyula Kiss, Gábor L. Kovács

Original papers, Volume 18, June, Issue 2

KEYWORDS: Dupuytren’s disease; active and advanced stages; monocytes; NK-T cells

https://doi.org/10.11613/BM.2008.019

Diagnostic value of BNP in diastolic heart failure

Serpil Eroglu, Huseyin Bozbas, Haldun Muderrisoglu

Review, Volume 18, June, Issue 2

KEYWORDS: brain natriuretic peptide; diastolic heart failure

https://doi.org/10.11613/BM.2008.018

Antibodies to citrullinated proteins/peptides in rheumatoid arthritis: what have we learned so far?

Andrea Tešija-Kuna, Marijana Žirović

Review, Volume 18, October, Issue 3

KEYWORDS: rheumatoid arthritis; citrullination; peptidylarginine deiminase; anti-CCP antibodies; anti-MCV antibodies

https://doi.org/10.11613/BM.2008.025

Molecular mechanisms and biochemical markers of acute pancreatitis

Krzysztof Celiński, Agnieszka Mądro

Review, Volume 18, June, Issue 2

KEYWORDS: acute pancreatitis; lipase; amilase; procalcitonin; CRP; interleukins

https://doi.org/10.11613/BM.2008.017

Molecular impact of glutathione peroxidases in antioxidant processes

Simona Jurkovič, Joško Osredkar, Janja Marc

Review, Volume 18, June, Issue 2

KEYWORDS: antioxidant process; glutathione peroxidase; SECIS motif; glutathione; selenium; isoenzymes

https://doi.org/10.11613/BM.2008.016

Confidence interval

Ana-Maria Simundic

Lessons in biostatistics, Volume 18, June, Issue 2

KEYWORDS: confidence interval; sample; standard error

https://doi.org/10.11613/BM.2008.015

Education of Masters of Science in Medical Biochemistry at the Faculty of Pharmacy and Biochemistry, University of Zagreb: How did we fit in the Bologne process

Tihana Žanić Grubišić

Editorial, Volume 18, June, Issue 2

https://doi.org/10.11613/BM.2008.014

Biochemia Medica indexed in Science Citation Index Expanded and Journal Citation Reports/Science Edition citation databases

Ana-Maria Simundic, Elizabeta Topić, Dubravka Čvorišćec

Editorial, Volume 18, June, Issue 2

https://doi.org/10.11613/BM.2008.013

How is metabolic syndrome related to dyslipidemia?

Victor H. Blaton, Irena Korita, Anyla Bulo

Review, Volume 18, February, Issue 1

KEYWORDS: metabolic syndrome; dyslipemia; HDL-cholesterol

https://doi.org/10.11613/BM.2008.003

Book review: Wendy Arneson, Jean Brickell: Clinical Chemistry - A Laboratory Perspective

Dunja Rogić

Opinion, Volume 18, February, Issue 1

Case report of hereditary hemorrhagic telangiectasia with severe anemia

Vesna Šupak, Lidija Bilić-Zulle, Antica Duletić-Načinović, Elizabeta Fišić

Case report, Volume 18, February, Issue 1

KEYWORDS: arteriovenous malformation; case report; iron-deficiency anemia; hereditary hemorrhagic telangiectasia

https://doi.org/10.11613/BM.2008.012

Helicobacter pylori seroprevalence in coronary artery disease

Mirjana Grozdovska-Naumoska, Vlatko Kotevski, Sonja Trojacanec-Piponska

Original papers, Volume 17, December, Issue 2

KEYWORDS: Helicobacter pylori; coronary artery disease; inflammation

https://doi.org/10.11613/BM.2007.018

Medical Laboratory Accreditation according to ISO 15189:2003. The Mexican Experience

Rosa Isabel Sierra-Amor, Maribel López-Martínez

Short review, Volume 17, December, Issue 2

KEYWORDS: accreditation; ISO 15189; medical laboratory

https://doi.org/10.11613/BM.2007.017

5th Croatian congress of medical biochemists with international participation 18.-22. October 2006., Poreč

Symposium abstracts, Volume 16, October, Suppl1

Thromboembolism in a 14-year-old boy – case report

Sandra Margetić, Biserka Raić, Tomislav Franjo Hajnžić, Nikola Bulj, Elizabeta Topić, Andrea Tešija-Kuna, Nora Nikolac

Case report, Volume 16, December, Issue 2

KEYWORDS: venous thromboembolism; antiphospholipid syndrome; PAI-1 polymorphism

https://doi.org/10.11613/BM.2006.018