A challenging laboratory case due to inappropriate sampling through an antiseptic barrier cap

Giovanni Introcaso, Giorgia Piras, Giorgia Mandelli, Sabrina Frisoli, Fabio Bottari

Preanalytical mysteries, Volume 36, June, Issue 2

KEYWORDS: alcohol contamination; analytical interferences; hematological analyzer; inappropriate sampling; preanalytical phase

https://doi.org/10.11613/BM.2026.021001

Extrapyramidal and anticholinergic reactions in an adolescent patient: a case for pharmacogenetic consideration

Iris Žunić Išasegi, Ivana Stefanović, Marta Okružnik Želalić, Livija Šimičević, Lana Ganoci, Maja Živković, Ivan Begovac, Nada Božina

Case reports, Volume 36, June, Issue 2

KEYWORDS: borderline personality traits; child and adolescent psychiatry; extrapyramidal symptoms; anticholinergic syndrome; pharmacogenetics

https://doi.org/10.11613/BM.2026.020902

The analytical impact of extracellular vesicles PSA on different commercial total PSA measurement methods

Ana Moreno, Amaia Sandúa, Roser Ferrer-Costa, Conxita Jacobs-Cacha, Nerea Varo, Javier Ancizu-Marckert, Jose Enrique Robles, Jose Luis Pérez Gracia, Estibaliz Alegre, Álvaro González

Original articles, Volume 36, February, Issue 1

KEYWORDS: prostate-specific antigen; extracellular vesicles; immunoassays; prostate cancer; evaluation

https://doi.org/10.11613/BM.2026.010703

Interfering heterophile antibodies as the cause of persistently falsely elevated high-sensitivity troponin I on Alinity i: a case report

Ivana Lapić, Dunja Rogić, Dragana Šegulja, Sandra Jakšić Jurinjak, Željka Vogrinc, Sanja Kačkov, Fran Smaić, Indira Imširović, Lovorka Đerek

Case reports, Volume 35, June, Issue 2

KEYWORDS: cardiology; troponin; immunoassay; heterophile antibodies; myocarditis

https://doi.org/10.11613/BM.2025.021001

Routine data analysis for moderate hemolysis interference correction in neuron specific enolase quantification

Leyre Ruiz, Tomás Munoz, Alvaro González, Estibaliz Alegre

Short communications, Volume 35, June, Issue 2

KEYWORDS: NSE; hemolysis; interference; correction formula

https://doi.org/10.11613/BM.2025.020802

Application and insights on patient-based real-time quality control: detecting undetected errors in internal quality control through daily antibody positivity rate analysis

Chaochao Ma, Qi Zhang, Yingying Hu, Wenyi Ding, Liangyu Xia, Ling Qiu

Short communications, Volume 35, June, Issue 2

KEYWORDS: Patient-Based Real-Time Quality Control; daily positivity rate; thyroid peroxidase antibody; systematic error; quality assessment

https://doi.org/10.11613/BM.2025.020801

National recommendations of the Working group for laboratory diagnostics of autoimmune diseases of the Croatian Society of Medical Biochemistry and Laboratory Medicine: Assessment of antineutrophil cytoplasmic antibodies (ANCA)

Ana Kozmar, Andrea Tešija Kuna, Nada Tomić Sremec, Lovorka Đerek, Vedrana Drvar, Katarina Gugo

Original articles, Volume 35, June, Issue 2

KEYWORDS: antineutrophil cytoplasmic antibodies; autoimmunity; harmonization; recommendations

https://doi.org/10.11613/BM.2025.020706

Bilirubin – new insights into an old molecule

Ivana Čepelak, Slavica Dodig, Ivan Pavić

Reviews, Volume 35, June, Issue 2

KEYWORDS: antioxidants; bilirubin; cell signalling; immunomodulation

https://doi.org/10.11613/BM.2025.020501

D-dimer assay interference detected by the discrepancy in D-dimer concentrations at different dilutions: a case report

Marija Milić, Dejana Brkić Barbarić, Iva Lukić, Mirna Kirin, Vikica Buljanović, Vatroslav Šerić

Preanalytical mysteries, Volume 34, October, Issue 3

KEYWORDS: D-dimer; heterophile antibodies; blood coagulation tests; interference

https://doi.org/10.11613/BM.2024.031001

Glucose inhibitor tubes in Croatian laboratories: are we doing well?

Alen Vrtarić, Nora Nikolac Gabaj, Ivana Ćelap

Short communications, Volume 34, October, Issue 3

KEYWORDS: preanalytical phase; glucose; glucose inhibitor; anticoagulants; citrate

https://doi.org/10.11613/BM.2024.030901

A modern overview of the process of platelet formation (thrombocytopoiesis) and its dependence on several factors

Anastasia Ivanovna Gabrilchak, Oksana Anatolievna Gusyakova, Vladimir Aleksandrovich Antipov, Elizabeth Alekseevna Medvedeva, Lyubov Leonidovna Tukshumskaya

Reviews, Volume 34, October, Issue 3

KEYWORDS: megakaryocyte; platelet; microenvironment; cytokines; apoptosis

https://doi.org/10.11613/BM.2024.030503

Two cases with discrepancy in the quantitative cytological assessment of cerebrospinal fluid in neonatal samples using light microscopy in comparison with Sysmex XN-1000

Pavel Broz, Simona Kukralova, Jana Palatova, Klara Kolduskova, Jana Zenkova, Daniel Rajdl, Jaroslav Racek

Case reports, Volume 34, June, Issue 2

KEYWORDS: biochemistry; cerebrospinal fluid; cytology; hematology; neonatology

https://doi.org/10.11613/BM.2024.020802

Antiphospholipid antibodies in patients with antiphospholipid syndrome

Slavica Dodig, Ivana Čepelak

Reviews, Volume 34, June, Issue 2

KEYWORDS: antiphospholipid syndrome; antiphospholipid antibodies; lupus anticoagulant; anti-β2-glycoprotein I; anticardiolipin antibodies

https://doi.org/10.11613/BM.2024.020504

Syndrome of inappropriate antidiuretic hormone secretion as an adverse reaction of ciprofloxacin: a case report and literature review

Luka Švitek, Barbara Grubišić, Ema Schonberger, Mihaela Zlosa, Dario Sabadi, Dubravka Lišnjić, Silvija Canecki-Varžić, Ines Bilić-Ćurčić, Sanja Mandić

Case reports, Volume 34, February, Issue 1

KEYWORDS: ciprofloxacin; inappropriate ADH syndrome; hyponatremia

https://doi.org/10.11613/BM.2024.010803

Interference of anti-nuclear antibodies on determination of anti-neutrophil cytoplasmic antibodies in patients suspected of vasculitis: a case series

Mala Mahto, Neha Rai, Pulak Ranjan Das, Saurabh Karmakar, Divendu Bhushan

Preanalytical mysteries, Volume 33, October, Issue 3

KEYWORDS: anti-neutrophil cytoplasmic antibodies; anti-nuclear antibodies; interference; indirect immunofluorescence

https://doi.org/10.11613/BM.2023.031001

False positive result of human chorionic gonadotropin caused by human anti-mouse antibodies

Jaroslav Racek, Ivana Potočová, Daniel Rajdl, Ladislav Trefil, Marie Šolcová

Case reports, Volume 33, February, Issue 1

KEYWORDS: anti-mouse antibodies; false positivity; hCG; interferences; pregnancy

https://doi.org/10.11613/BM.2023.010802

Laboratory medicine in arterial hypertension

Merica Aralica, Vesna Šupak-Smolčić, Lorena Honović, Lucija Franin, Pavica Šonjić, Maja Šimac, Mihovil Horvat, Nina Poropat

Reviews, Volume 33, February, Issue 1

KEYWORDS: antihypertensive agent; clinical laboratory test; hypertension; medical laboratory science

https://doi.org/10.11613/BM.2023.010501

A novel approach for more precise quantification of M-protein using variables derived from immunosubtraction electropherogram and associated biochemistry analytes

Dragana Šegulja, Danica Matišić, Karmela Barišić, Dunja Rogić

Original articles, Volume 32, October, Issue 3

KEYWORDS: capillary electrophoresis; M-protein; monoclonal gammopathy; multiple myeloma; serum protein electrophoresis; immunosubtraction electrophoresis

https://doi.org/10.11613/BM.2022.030703

Lipoproteins and cholesterol homeostasis in paediatric nephrotic syndrome patients

Yonas Mulat Simachew, Tamara Antonić, Tamara Gojković, Sandra Vladimirov, Marija Mihajlović, Sanja Vujčić, Gordana Miloševski-Lomić, Jelena Vekić, Aleksandra Zeljković, Vesna Spasojević-Kalimanovska, Amira Peco-Antić, Dušan Paripović, Aleksandra Stefanović

Original articles, Volume 32, June, Issue 2

KEYWORDS: paediatric nephrotic syndrome; glucocorticoid therapy; serum lipid profile; non-cholesterol sterols

https://doi.org/10.11613/BM.2022.020706

Corrigendum to: Assessment of antinuclear antibodies (ANA): National recommendations on behalf of the Croatian society of medical biochemistry and laboratory medicine

Andrea Tešija Kuna, Lovorka Đerek, Vedrana Drvar, Ana Kozmar, Katarina Gugo

Erratum, Volume 32, February, Issue 1

https://doi.org/10.11613/BM.2022.011201

Dynamic profiles and predictive values of some biochemical and haematological quantities in COVID-19 inpatients

María José Castro-Castro, Laura García-Tejada, Ariadna Arbiol-Roca, Lourdes Sánchez-Navarro, Loreto Rapún-Mas, Isabel Cachon-Suárez, Marta Álvarez-Álvarez, Dolors Dot-Bach, Roser Güell-Miró, Anna Cortés-Bosch de Bassea, Macarena Dastis-Arias, Ana Sancho-Cerro, Noelia Díaz-Troyano, Teresa Escartín-Diez, Diego Muñoz-Provencio, Rosa Navarro-Badal

Original articles, Volume 32, February, Issue 1

KEYWORDS: COVID-19; pneumonia; prognosis; SARS-CoV-2

https://doi.org/10.11613/BM.2022.010706

Seroprevalence of SARS-CoV-2 in Croatian solid-organ transplant recipients

Anna Mrzljak, Željka Jureković, Jadranka Pavičić-Šarić, Vladimir Stevanović, Irena Tabain, Željka Hruškar, Danko Mikulić, Ljubo Barbić, Tatjana Vilibić-Čavlek

Short Communications, Volume 31, October, Issue 3

KEYWORDS: COVID-19; seroprevalence; solid-organ transplant recipients; SARS-CoV-2 antibodies

https://doi.org/10.11613/BM.2021.030901

The comparison of the three assays for determination of fecal calprotectin in inflammatory bowel disease

Joško Osredkar, Tina Kurent, Teja Fabjan, Kristina Kumer, Elizabeta Božnar Alič, David Drobne

Original Articles, Volume 31, June, Issue 2

KEYWORDS: inflammatory bowel disease; feces; biomarkers; leukocyte L1 antigen complex

https://doi.org/10.11613/BM.2021.020707

Seroprevalence of SARS-CoV-2 infection among children in Children’s Hospital Zagreb during the initial and second wave of COVID-19 pandemic in Croatia

Jasna Lenicek Krleza, Renata Zrinski Topic, Vladimir Stevanovic, Amarela Lukic-Grlic, Irena Tabain, Zrinjka Misak, Goran Roic, Bernard Kaic, Dijana Mayer, Zeljka Hruskar, Ljubo Barbic, Tatjana Vilibic-Cavlek

Original Articles, Volume 31, June, Issue 2

KEYWORDS: COVID-19; SARS-CoV-2; anti-SARS-CoV-2 antibodies; children; seroprevalence

https://doi.org/10.11613/BM.2021.020706

Utility of icteric index in clinical laboratories: more than a preanalytical indicator

Rufino Mondejar, María Mayor Reyes, Enrique Melguizo Madrid, Consuelo Cañavate Solano, Santiago Pérez Ramos

Original Articles, Volume 31, June, Issue 2

KEYWORDS: jaundice; bilirubin; hyperbilirubinemia; haemolysis; receiver operating characteristic curve

https://doi.org/10.11613/BM.2021.020703

Current status of the lateral flow immunoassay for the detection of SARS-CoV-2 in nasopharyngeal swabs

Anita Somborac Bačura, Marija Dorotić, Leonarda Grošić, Monika Džimbeg, Slavica Dodig

Short Review, Volume 31, June, Issue 2

KEYWORDS: COVID-19; immunoassay; nasopharynx; SARS-CoV-2 antigen testing

https://doi.org/10.11613/BM.2021.020601

Assessment of antinuclear antibodies (ANA): National recommendations on behalf of the Croatian society of medical biochemistry and laboratory medicine

Andrea Tešija Kuna, Lovorka Đerek, Vedrana Drvar, Ana Kozmar, Katarina Gugo

Review, Volume 31, June, Issue 2

KEYWORDS: antinuclear antibodies; autoimmunity; recommendations; harmonization

https://doi.org/10.11613/BM.2021.020502

Pre-amplification as a method for improvement of quantitative RT-PCR analysis of circulating miRNAs

Ankica Sekovanić, Adrijana Dorotić, Jasna Jurasović, Daria Pašalić, Jelena Kovačić, Sandra Stasenko, Tatjana Mioč, Martina Piasek, Tatjana Orct

Short Communications, Volume 31, February, Issue 1

KEYWORDS: blood plasma; circulating microRNAs; epigenetics; pre-amplification; RT-PCR

https://doi.org/10.11613/BM.2021.010901

Antipsychotics-induced hyperprolactinemia and screening for macroprolactin

Nedjeljka Ruljancic, Ana Bakliza, Sandra Vuk Pisk, Natko Geres, Katarina Matic, Ena Ivezic, Vladimir Grosic, Igor Filipcic

Original Articles, Volume 31, February, Issue 1

KEYWORDS: biochemistry; hyperprolactinemia; macroprolactin; prolactin

https://doi.org/10.11613/BM.2021.010707

Comparison of a rapid immunochromatographic test with a chemiluminescence immunoassay for detection of anti-SARS-CoV-2 IgM and IgG

Caterina Maria Gambino, Bruna Lo Sasso, Claudia Colomba, Rosaria Vincenza Giglio, Luisa Agnello, Giulia Bivona, Marcello Ciaccio

Short communication, Volume 30, October, Issue 3

KEYWORDS: COVID-19; serological test; antibodies; CLIA; immunochromatography

https://doi.org/10.11613/BM.2020.030901

Chromogenic anti-FXa assay calibrated with low molecular weight heparin in patients treated with rivaroxaban and apixaban: possibilities and limitations

Sandra Margetić, Ivana Ćelap, Diana Delić Brkljačić, Nikola Pavlović, Sandra Šupraha Goreta, Ivana Kobasić, Arijana Lovrenčić-Huzjan, Vanja Bašić Kes

Original Articles, Volume 30, February, Issue 1

KEYWORDS: apixaban; DOAC; factor Xa inhibitors; LMWH; rivaroxaban

https://doi.org/10.11613/BM.2020.010702

Rapid serum tube technology overcomes problems associated with use of anticoagulants

Kong-Nan Zhao, Goce Dimeski, John de Jersey, Lambro A Johnson, Michael Grant, Paul P Masci, Martin F Lavin

Original Articles, Volume 29, October, Issue 3

KEYWORDS: prothrombin activators; serum; anticoagulants; analytes

https://doi.org/10.11613/BM.2019.030706

Rewarding the quantity of peer review could harm biomedical research

Aceil Al-Khatib, Jaime A. Teixeira da Silva

Research integrity corner, Volume 29, June, Issue 2

KEYWORDS: autonomy; biomedical research; ethics in publishing; responsible peer review; scientific misconduct

https://doi.org/10.11613/BM.2019.020201

Effects of different anticoagulants on glycated albumin quantification

Graziella Bonetti, Nicola Di Gaetano, Renata Paleari, Ferruccio Ceriotti

Short Communications, Volume 29, February, Issue 1

KEYWORDS: preanalytical phase; serum albumin; diabetes mellitus; anticoagulants

https://doi.org/10.11613/BM.2019.010901

Confidence interval for quantiles and percentiles

Cristiano Ialongo

Lessons in Biostatistics, Volume 29, February, Issue 1

KEYWORDS: biostatistics; statistical methods; confidence intervals; extra-analytical phase

https://doi.org/10.11613/BM.2019.010101

Reducing test request for anti-thyroglobulin and anti-thyroid peroxidase antibodies: trends before and after interventions based on rejection rules and profile management

Pedro Sánchez Pellicer, Ruth González Tamayo, Vicente Navarro López

Original Papers, Volume 28, October, Issue 3

KEYWORDS: demand management laboratory; test laboratory request; anti-thyroid antibodies; anti-thyroid peroxidase antibodies; anti-thyroglobulin antibodies

https://doi.org/10.11613/BM.2018.030709

Detection of annexin A8 antibodies in serum of patients with antiphospholipid syndrome

Philipp Scholz, Markus Auler, Johannes Ruthard, Bent Brachvogel, Andreas R. Klatt, Thomas Streichert

Original Papers, Volume 28, October, Issue 3

KEYWORDS: annexin A8; antiphospholipid syndrome; antiphospholipid antibodies

https://doi.org/10.11613/BM.2018.030703

The impact of delayed sample handling and type of anticoagulant on the interpretation of dysplastic signs detected by flow cytometry

Bettina Kárai, Zsófia Miltényi, Lajos Gergely, Marianna Száraz-Széles, János Kappelmayer, Zsuzsanna Hevessy

Original Papers, Volume 28, June, Issue 2

KEYWORDS: myelodysplastic syndromes; flow cytometry; pre-analytical error

https://doi.org/10.11613/BM.2018.020704

Diagnostic value of tumour markers in pleural effusions

Darian Volarić, Veljko Flego, Gordana Žauhar, Ljiljana Bulat-Kardum

Original Papers, Volume 28, February, Issue 1

KEYWORDS: pleural effusion; CA-125 antigen; carcinoembryonic antigen; neuron-specific enolase; cytokeratin 19 fragment

https://doi.org/10.11613/BM.2018.010706

Analytical evaluation of a fully automated immunoassay for faecal calprotectin in a paediatric setting

Britta Noebauer, Lejla Ramic, Andrea Konstantin, Christina Zachbauer, Elisa Einwallner

Original Papers, Volume 27, October, Issue 3

KEYWORDS: calprotectin; faeces; particle-enhanced turbidimetric immunoassay (PETIA); inflammatory bowel disease

https://doi.org/10.11613/BM.2017.030710

Testing lupus anticoagulants in a real-life scenario - a retrospective cohort study

Franz Ratzinger, Tanja Panic, Helmuth Haslacher, Thomas Perkmann, Klaus G. Schmetterer, Sabine Belik, Georg Maenner, Ingrid Pabinger, Peter Quehenberger

Original Papers, Volume 27, October, Issue 3

KEYWORDS: blood coagulation; blood coagulation tests; lupus coagulation inhibitor; partial thromboplastin time

https://doi.org/10.11613/BM.2017.030705

Pneumatic tube system transport does not alter platelet function in optical and whole blood aggregometry, prothrombin time, activated partial thromboplastin time, platelet count and fibrinogen in patients on anti-platelet drug therapy

Dietmar Enko, Harald Mangge, Andreas Münch, Tobias Niedrist, Elisabeth Mahla, Helfried Metzler, Florian Prüller

Original Papers, Volume 27, February, Issue 1

KEYWORDS: platelets; platelet aggregation; platelet function tests; clinical laboratory services; preanalytical phase

https://doi.org/10.11613/BM.2017.023

Misleading FT4 measurement: Assay-dependent antibody interference

Ingrid Revet, Lianne SM Boesten, Jan Linthorst, Elif Yildiz, Johannes W Janssen, Yolanda B de Rijke, Arjan Albersen

Case Report, Volume 26, October, Issue 3

KEYWORDS: FT4; thyroid function test; diagnostic errors; interference; immunoassay

https://doi.org/10.11613/BM.2016.046

Current practice in laboratory diagnostics of autoimmune diseases in Croatia. 
Survey of the Working group for laboratory diagnostics of autoimmune diseases of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Andrea Tešija Kuna, Lovorka Đerek, Ana Kozmar, Vedrana Drvar

Original Papers, Volume 26, October, Issue 3

KEYWORDS: autoimmune diseases; autoantibodies; survey

https://doi.org/10.11613/BM.2016.041

Concurrent acquired inhibitors to factor VIII and IX, a laboratory artifact: a case report

Saša Anžej Doma, Andreas Hillarp, Tadej Pajič, Dušan Andoljšek, Peter Černelč, Irena Preldžnik Zupan

Case Report, Volume 26, June, Issue 2

KEYWORDS: inhibitor; autoantibody; blood coagulation factor; enzyme-linked immunosorbent assay

https://doi.org/10.11613/BM.2016.033

Detection of multiple annexin autoantibodies in a patient with recurrent miscarriages, fulminant stroke and seronegative antiphospholipid syndrome

Philipp Scholz, Markus Auler, Bent Brachvogel, Thomas Benzing, Peter Mallman, Thomas Streichert, Andreas R. Klatt

Case Report, Volume 26, June, Issue 2

KEYWORDS: annexin; anti-phospholipid syndrome; anti-phospholipid antibody syndrome; seronegative anti-phospholipid syndrome; recurrent miscarriage

https://doi.org/10.11613/BM.2016.032

The use of S-Monovette is effective to reduce the burden of hemolysis in a large urban emergency department

Giuseppe Lippi, Patrizia Bonelli, Laura Bonfanti, Gianfranco Crevellin

Original papers, Volume 25, February, Issue 1

KEYWORDS: preanalytical phase; hemolysis; blood specimen collection; catheter; emergency department

https://doi.org/10.11613/BM.2015.008

Determination of reference interval for presepsin, an early marker for sepsis

Davide Giavarina, Mariarosa Carta

Original papers, Volume 25, February, Issue 1

KEYWORDS: CD14 Antigen; presepsin; reference values; male; female; Clinical and Laboratory Standard Institute

https://doi.org/10.11613/BM.2015.007

Detection of acute kidney injury in premature asphyxiated neonates by serum neutrophil gelatinase-associated lipocalin (sNGAL) – sensitivity and specificity of a potential new biomarker

Biljana Pejović, Jelena Erić-Marinković, Marija Pejović, Jelena Kotur-Stevuljević, Amira Peco-Antić

Original papers, Volume 25, October, Issue 3

KEYWORDS: serum neutrophil gelatinase-associated lipocalin; acute kidney injury; premature neonates; biomarker

https://doi.org/10.11613/BM.2015.046

“Real life use” of troponin in the emergency department: a survey of over 3000 cases

Matteo Vidali, Enrica Verzotti, Nicole Cabraz, Francesca Santi, Alessia Puma, Giorgio Bellomo, Alessandro Lupi, Giuseppe Lippi, Gian Carlo Avanzi

Original papers, Volume 25, October, Issue 3

KEYWORDS: troponin I; acute coronary syndrome; emergency service; hospital; chest pain

https://doi.org/10.11613/BM.2015.043

ICMJE authorship criteria are not met in a substantial proportion of manuscripts submitted to Biochemia Medica

Vesna Šupak-Smolčić, Ana Mlinarić, Dragana Antončić, Martina Horvat, Jelena Omazić, Ana-Maria Šimundić

Research integrity corner, Volume 25, October, Issue 3

KEYWORDS: authorship; acknowledgement; research integrity; editorial practice

https://doi.org/10.11613/BM.2015.033

Cost-effectiveness analysis of acute kidney injury biomarkers in pediatric cardiac surgery

Stanislava Petrovic, Natasa Bogavac-Stanojevic, Dragana Lakic, Amira Peco-Antic, Irena Vulicevic, Ivana Ivanisevic, Jelena Kotur-Stevuljevic, Zorana Jelic-Ivanovic

Research Article, Volume 25, June, Issue 2

KEYWORDS: acute kidney injury; cardiac surgery; children; biomarkers; cost effectiveness analysis

https://doi.org/10.11613/BM.2015.027

Liver transplantation reverses hypergammaglobulinemia in patients with chronic hepatic failure

Diana Lebherz-Eichinger, Remy Schwarzer, Michael C. Motal, Daniel A. Klaus, Andreas Mangold, Hendrik J. Ankersmit, Gabriela A. Berlakovich, Claus G. Krenn, Georg A. Roth

Research Article, Volume 25, June, Issue 2

KEYWORDS: antibodies; immunoglobulins; liver failure; liver transplantation; artificial liver support system; molecular adsorbent recirculating system

https://doi.org/10.11613/BM.2015.026

Plasma centrifugation does not influence thrombin-antithrombin and plasmin-antiplasmin levels but determines platelet microparticles count

Ewa Stępień, Krzysztof Gruszczyński, Przemysław Kapusta, Artur Kowalik, Iwona Wybrańska

Research Article, Volume 25, June, Issue 2

KEYWORDS: cell-derived microparticles; blood coagulation tests; centrifugation; preanalytical phase

https://doi.org/10.11613/BM.2015.022

Unusually difficult clinical presentation of an infant suffering from congenital cytomegalovirus (CMV) infection combined with alpha 1-antitrypsin (A1AT) deficiency

Ines Potočnjak, Goran Tešović, Andrea Tešija Kuna, Mario Štefanović, Orjena Žaja

Case report, Volume 24, October, Issue 3

KEYWORDS: cytomegalovirus infections; congenital; alpha 1-antitrypsin deficiency; ganciclovir

https://doi.org/10.11613/BM.2014.043

Is an integrative laboratory algorithm more effective in detecting аlpha-1-antitrypsin deficiency in patients with premature chronic obstructive pulmonary disease than AAT concentration based screening approach?

Andjelo Beletic, Aleksandra Dudvarski-Ilic, Branislava Milenkovic, Ljudmila Nagorni-Obradovic, Mila Ljujic, Valentina Djordjevic, Dusko Mirkovic, Dragica Radojkovic, Nada Majkic-Singh

Original papers, Volume 24, June, Issue 2

KEYWORDS: alpha-1-antitrypsin deficiency; diagnostic techniques and procedures; pulmonary disease; chronic obstructive

https://doi.org/10.11613/BM.2014.032

Oxidative status parameters in children with urinary tract infection

Stanislava Petrovic, Natasa Bogavac-Stanojevic, Jelena Kotur-Stevuljevic, Amira Peco-Antic, Ivana Ivanisevic, Jasmina Ivanisevic, Dusan Paripovic, Zorana Jelic-Ivanovic

Original papers, Volume 24, June, Issue 2

KEYWORDS: oxidative stress; inflammation; acute kidney injury

https://doi.org/10.11613/BM.2014.029

History of the preanalytical phase: a personal view

Walter G. Guder

Review, Volume 24, February, Issue 1

KEYWORDS: influence factors; interference factors; preanalytical factors; amylase in urine; haemolytic samples; anticoagulants; blood collection tubes; centrifugation

https://doi.org/10.11613/BM.2014.005

Pharmacogenetics and personalized treatment of type 2 diabetes

Sabina Semiz, Tanja Dujic, Adlija Causevic

Review, Volume 23, June, Issue 2

KEYWORDS: type 2 diabetes mellitus; pharmacogenomics; pharmacogenetics; oral antidiabetic drugs; personalized medicine

https://doi.org/10.11613/BM.2013.020

Concentration and content

Xavier Fuentes-Arderiu

Editorial, Volume 23, June, Issue 2

KEYWORDS: concentration; content; quantity; metrology; terminology

https://doi.org/10.11613/BM.2013.017

Accidental digitoxin intoxication: an interplay between laboratory and clinical medicine

Luigi M. Castello, Sophie Negro, Francesca Santi, Isabella Zanotti, Matteo Vidali, Marco Bagnati, Giorgio Bellomo, Gian Carlo Avanzi

Case report, Volume 22, October, Issue 3

KEYWORDS: digitalis glycosides/poisoning; digitoxin; digoxin antibodies Fab fragments; digitoxin/toxicity; digitoxin/analysis

https://doi.org/10.11613/BM.2012.040

Gamma heavy chain disease in a patient with rheumatoid arthritis – a laboratory evaluation

Luigi M. Castello, Sophie Negro, Francesca Santi, Isabella Zanotti, Matteo Vidali, Marco Bagnati, Giorgio Bellomo, Gian Carlo Avanzi

Case report, Volume 22, October, Issue 3

KEYWORDS: heavy chain disease; arthritis; rheumatoid; immunoglobulin gamma-chains; electrophoresis; electrophoresis; capillary

https://doi.org/10.11613/BM.2012.039

Serum thyroglobulin antibody levels within or near to the reference range may interfere with thyroglobulin measurement.

Zoltan Locsei, Istvan Szabolcs, Karoly Racz, Gabor L. Kovacs, Dora Horvath, Erzsebet Toldy

Original papers, Volume 22, October, Issue 3

KEYWORDS: antibody interference; thyroglobulin; thyroglobulin antibodies; assay

https://doi.org/10.11613/BM.2012.038

The new oral anticoagulants and the future of haemostasis laboratory testing

Emmanuel J. Favaloro, Giuseppe Lippi

Review, Volume 22, October, Issue 3

KEYWORDS: haemostasis; coagulation; laboratory tests; anticoagulants; anti-thrombotics; Dabigatran; Rivaroxaban.

https://doi.org/10.11613/BM.2012.035

Taxonomy of quantities

Xavier Fuentes-Arderiu

Editorial, Volume 22, October, Issue 3

KEYWORDS: quantity; nomenclature; terminology; taxonomy; property

https://doi.org/10.11613/BM.2012.030

The organisation of an educational program for specialists in clinical chemistry by the Greek Society of Clinical Chemistry-Clinical Biochemistry

Demetrios Rizos, Photini Karababa, Angeliki Sarandakou, Othon Panagiotakis, Alexander Haliassos, Konstantinos Makris, Katerina Psarra, Eleni Bairaktari, Panagiota Spyropoulou, Chara Nikolou, Nikolaos Galiatsatos, Nikolaos Trakas, Angeliki Ferderigou, Kons

Special issue, Volume 21, February, Issue 1

KEYWORDS: clinical chemistry; education; Register; EC4

https://doi.org/10.11613/BM.2011.007

Neutrophil CD64 as a sepsis biomarker

Johannes J.M.L. Hoffmann

Special issue, Volume 21, October, Issue 3

KEYWORDS: biomarker; CD64 antigen; flow cytometry; infection; neutrophil; sepsis

https://doi.org/10.11613/BM.2011.038

Neonatal sepsis

Iva Mihatov Stefanovic

Special issue, Volume 21, October, Issue 3

KEYWORDS: infection; neonate; sepsis; antibiotics

https://doi.org/10.11613/BM.2011.037

Anti-Müllerian hormone: A unique biochemical marker of gonadal development and fertility in humans

Ivana Zec, Dubravka Tislaric-Medenjak, Zeljka Bukovec Megla, Ivana Kucak

Review, Volume 21, October, Issue 3

KEYWORDS: anti-Müllerian hormone; ovarian reserve; spermatogenesis; infertility; sex-differentiation

https://doi.org/10.11613/BM.2011.031

Impaired oxidative balance and association of blood glucose, insulin and HOMA-IR index in migraine

Necat Yilmaz, Ozgur Aydin, Aysenur Yegin, Aysun Tiltak, Esin Eren, Guzin Aykal

Original papers, Volume 21, June, Issue 2

KEYWORDS: migraine; oxidant; antioxidant; HOMA index; oxidative stress.

https://doi.org/10.11613/BM.2011.023

Increased IgA in a subject with positive anti-thyroid autoantibodies - a case report

Slavica Dodig, Renata Zrinski Topić, Jadranka Demirović, Jadranka Živčić

Case report, Volume 20, February, Issue 1

KEYWORDS: IgA; immunoassay; interferences; thyroid disease; autoantibody

https://doi.org/10.11613/BM.2010.012

Comparison of two immunoassays for CA19-9, CEA and AFP tumor markers

Adriana Unić, Lovorka Đerek, Nevenka Stančin, Tihana Serdar, Novka Šprajc, Željko Romić

Original papers, Volume 20, February, Issue 1

KEYWORDS: tumor markers; carbohydrate antigen 19-9; alpha-fetoprotein; carcinoembryonic antigen; immunoassay

https://doi.org/10.11613/BM.2010.010

Laboratory diagnosis of autoimmune diseases – new technologies, old dilemmas

Ilza Salamunić

Review, Volume 20, February, Issue 1

KEYWORDS: autoimmune diseases; autoantibodies; diagnostics; technologies; standardization

https://doi.org/10.11613/BM.2010.006

Prolactin response in patients with schizophrenia treated with haloperidol, clozapine, risperidone and olanzapine

Jelena Potkonjak, Dalibor Karlović, Željka Bukovec, Tihana Baričević

Original papers, Volume 19, February, Issue 1

KEYWORDS: dopamine; prolactin; schizophrenia; serotonin; antipsychotics drugs

https://doi.org/10.11613/BM.2009.007

Monitoring chronic myeloid leukemia patients responding to treatment with tyrosine kinase inhibitors by real-time quantitative polymerase chain reaction

Margareta Radić Antolic, Renata Zadro, Dubravka Sertić, Boris Labar

Original papers, Volume 19, February, Issue 1

KEYWORDS: chronic myeloid leukemia; imatinib mesylate; quantitative polymerase chain reaction; major molecular response

https://doi.org/10.11613/BM.2009.006

Interferences in quantitative immunochemical methods

Slavica Dodig

Review, Volume 19, February, Issue 1

KEYWORDS: immunoassays; interferences; cross-reactivity; prozone effect

https://doi.org/10.11613/BM.2009.005

5’-nucleotidase, oxidative stress and antioxidant status in alcohol consumers and cirrhotic patients

Tarannum F. Subhani, Mohammad A. Nasar, Abdalla Jarrari, Vivian D’Souza, Mohammad A. Naseer, Faiyaz Shakeel

Original papers, Volume 19, October, Issue 3

KEYWORDS: alcohol consumers; antioxidant effects; 5’-nucleotidase; oxidative stress

https://doi.org/10.11613/BM.2009.026

Maternal and cord blood malondialdehyde and antioxidant vitamin levels in normal and preeclamptic women

Mohd Suhail, Mohd Faizul-Suhail

Original papers, Volume 19, June, Issue 2

KEYWORDS: maternal plasma; cord plasma; malondialdehyde; anti-oxidant vitamins; pregnancy; preeclampsia

https://doi.org/10.11613/BM.2009.017

Hepatotoxicity of antituberculosis drugs in a mother and a child affected by pulmonary tuberculosis - A case report

Slavica Dodig, Miljenko Raos, Ivka Zoričić-Letoja

Case report, Volume 18, February, Issue 1

KEYWORDS: antituberculosis drugs; hepatotoxicity; tuberculosis; child

https://doi.org/10.11613/BM.2008.011

Comparative analysis of multiplex AtheNA Multi-Lyte ANA test system and conventional laboratory methods to detect autoantibodies

Ilza Salamunić, Branka Pauković Sekulić, Adela Galetović, Leida Tandara, Dušanka Martinović Kaliterna

Original papers, Volume 18, February, Issue 1

KEYWORDS: antinuclear antibodies; AtheNA Multi-Lyte ANA test system; ELISA; autoimmune diseases

https://doi.org/10.11613/BM.2008.010

Quantitative in situ hybridization with enhanced sensitivity in soft, bone and tooth tissue using digoxigenin tagged RNA probes

Jelica Gluhak-Heinrich, Wuchen Yang, Marie A. Harris, Stephen E. Harris

Original papers, Volume 18, February, Issue 1

KEYWORDS: quantitative in situ hybridization; digoxigenin probes; paraffin embedded bone tissue

https://doi.org/10.11613/BM.2008.008

Biomarkers of enzymatic and non-enzymatic antioxidative defense in type 2 diabetes mellitus – comparative analysis

Emina Čolak, Vesna Dimitrijević-Srećković, Predrag B. Djordjević, Sanja Stanković, Biljana Glišić, Branko Srećković, Nada Majkić-Singh

Original papers, Volume 18, February, Issue 1

KEYWORDS: oxidative stress; antioxidant defense; type 2 diabetes mellitus; cardiovascular complications; comparative analysis

https://doi.org/10.11613/BM.2008.006

Alterations in antioxidant and pro-oxidant balance in preeclampsia – impact on erythrocyte osmotic fragility

Mohd Suhail, Mohd Faizul Suhail, Hina Khan

Original papers, Volume 18, October, Issue 3

KEYWORDS: preeclampsia; nonenzymatic antioxidants and oxidants; enzymatic antioxidants; erythrocyte osmotic fragility

https://doi.org/10.11613/BM.2008.029

Determination of D-dimer by different quantitative assays – A harmonization exercise

Mojca Stegnar, Mojca Božič

Original papers, Volume 18, June, Issue 2

KEYWORDS: D-dimer; harmonization; validation

https://doi.org/10.11613/BM.2008.022

Flow cytometric differentiation of the origin of hematuria using fluorescent antiglycophorin antibody

Marija Miloš, Gordana Boršo, Dubravka Čvorišćec

Original papers, Volume 18, June, Issue 2

KEYWORDS: glomerular hematuria; non-glomerular hematuria; flow cytometry

https://doi.org/10.11613/BM.2008.021

Antibodies to citrullinated proteins/peptides in rheumatoid arthritis: what have we learned so far?

Andrea Tešija-Kuna, Marijana Žirović

Review, Volume 18, October, Issue 3

KEYWORDS: rheumatoid arthritis; citrullination; peptidylarginine deiminase; anti-CCP antibodies; anti-MCV antibodies

https://doi.org/10.11613/BM.2008.025

Molecular impact of glutathione peroxidases in antioxidant processes

Simona Jurkovič, Joško Osredkar, Janja Marc

Review, Volume 18, June, Issue 2

KEYWORDS: antioxidant process; glutathione peroxidase; SECIS motif; glutathione; selenium; isoenzymes

https://doi.org/10.11613/BM.2008.016

Case report of hereditary hemorrhagic telangiectasia with severe anemia

Vesna Šupak, Lidija Bilić-Zulle, Antica Duletić-Načinović, Elizabeta Fišić

Case report, Volume 18, February, Issue 1

KEYWORDS: arteriovenous malformation; case report; iron-deficiency anemia; hereditary hemorrhagic telangiectasia

https://doi.org/10.11613/BM.2008.012

Severe cholestasis in a newborn with PiZZ alpha-1-antitrypsin genotype – A case report

Marijana Žirović, Andrea Tešija Kuna, Nora Nikolac, Mario Štefanović, Elizabeta Topić, Orjena Žaja-Franulović, Zvonimir Jurčić

Case report, Volume 17, December, Issue 2

https://doi.org/10.11613/BM.2007.024

Metabolic side-effects of novel antipsychotic drugs

Ana Kovak-Mufić, Dalibor Karlović, Marko Martinac, Darko Marčinko, Katica Letinić, Branka Vidrih

Review, Volume 17, December, Issue 2

KEYWORDS: metabolic syndrome; side-effects; antipsychotics; lipid metabolism; glucose metabolism

https://doi.org/10.11613/BM.2007.016

Comparison of sensitivity of nested PCR and quantitative PCR in Bcr-Abl p210 transcript detection in chronic myelogenous leukemia

Maruška Marušić Vrsalović, Rajko Kušec, Vlatko Pejša, Željko Romić

Original papers, Volume 17, June, Issue 1

KEYWORDS: nPCR; qPCR; sensitivity; p210 detection

https://doi.org/10.11613/BM.2007.012

Thromboembolism in a 14-year-old boy – case report

Sandra Margetić, Biserka Raić, Tomislav Franjo Hajnžić, Nikola Bulj, Elizabeta Topić, Andrea Tešija-Kuna, Nora Nikolac

Case report, Volume 16, December, Issue 2

KEYWORDS: venous thromboembolism; antiphospholipid syndrome; PAI-1 polymorphism

https://doi.org/10.11613/BM.2006.018

Vitamin C in disease prevention and therapy

Robert Domitrović

Review, Volume 16, December, Issue 2

KEYWORDS: vitamin C; antioxidant; cardiovascular disease; cancer; common cold; respiratory diseases; diabetes mellitus; cataract

https://doi.org/10.11613/BM.2006.011