Archive (1991-2005)

Original papers, Volume 15, February, Issue Archive

Pre-analytical mysteries: A case of severe hypervitaminosis D and mild hypercalcaemia

Emma Whittle, Elzahn de Waal, Tony Huynh, Oliver Treacy, Adam Morton

Short Communications, Volume 31, Articles ahead of print

KEYWORDS: endocrinology; hypercalcaemia; hypervitaminosis D; interferences; paraprotein

https://doi.org/10.11613/BM.2021.011001

Pre-amplification as a method for improvement of quantitative RT-PCR analysis of circulating miRNAs

Ankica Sekovanić, Adrijana Dorotić, Jasna Jurasović, Daria Pašalić, Jelena Kovačić, Sandra Stasenko, Tatjana Mioč, Martina Piasek, Tatjana Orct

Short Communications, Volume 31, Articles ahead of print

KEYWORDS: blood plasma; circulating microRNAs; epigenetics; pre-amplification; RT-PCR

https://doi.org/10.11613/BM.2021.010901

Antipsychotics-induced hyperprolactinemia and screening for macroprolactin

Nedjeljka Ruljancic, Ana Bakliza, Sandra Vuk Pisk, Natko Geres, Katarina Matic, Ena Ivezic, Vladimir Grosic, Igor Filipcic

Original Articles, Volume 31, Articles ahead of print

KEYWORDS: biochemistry; hyperprolactinemia; macroprolactin; prolactin

https://doi.org/10.11613/BM.2021.010707

Detection and correction of incomplete duplicate 24-hour urine collections – theory and practical evidence

Raymond W Wulkan, Martin van der Horst

Original Articles, Volume 31, Articles ahead of print

KEYWORDS: urine specimen collection; creatinine/urine; patient compliance

https://doi.org/10.11613/BM.2021.010706

Utilization of biological variation data in the interpretation of laboratory test results – survey about clinicians’ opinion and knowledge

Humeyra Ozturk Emre, Fatma Hande Karpuzoglu, Cihan Coskun, Ebru Demirel Sezer, Ozlem Goruroglu Ozturk, Fatma Ucar, Hikmet Can Cubukcu, Fatma Demet Arslan, Levent Deniz, Mehmet Senes, Mustafa Serteser, Cevat Yazici, Dogan Yucel, Abdurrahman Coskun

Original Articles, Volume 31, Articles ahead of print

KEYWORDS: biological variation; laboratory error; patient safety; reference change value

https://doi.org/10.11613/BM.2021.010705

Effect of haemolysis on an enzymatic measurement of ethanol

Abdulkadir Çat, Kamil Taha Uçar, Alper Gümüş

Original Articles, Volume 31, Articles ahead of print

KEYWORDS: ethanol; haemolysis; interference; preanalytical error

https://doi.org/10.11613/BM.2021.010704

Using clinical guidelines to assess the potential value of laboratory medicine in clinical decision-making

Allan J. Hicks, Zoe L. Carwardine, Mike J. Hallworth, Eric S. Kilpatrick

Original Articles, Volume 31, Articles ahead of print

KEYWORDS: cardiovascular diseases; guideline; clinical laboratory testing

https://doi.org/10.11613/BM.2021.010703

Women in sports: the applicability of common national reference intervals for inflammatory and coagulation biomarkers (HemSter Study)

Vanja Radišić Biljak, Valentina Vidranski, Lana Ružić, Ana-Maria Simundic, Tihomir Vidranski

Original Articles, Volume 31, Articles ahead of print

KEYWORDS: sports; international physical activity questionnaire short form (IPAQ-SF); inflammation; blood coagulation; reference ranges

https://doi.org/10.11613/BM.2021.010702

Evaluation of a new equation for estimating low-density lipoprotein cholesterol through the comparison with various recommended methods

Eduardo Martínez-Morillo, María García-García, María Angeles Luengo Concha, Luis Rello Varas

Original Articles, Volume 31, Articles ahead of print

KEYWORDS: cholesterol; equation; evaluation; low-density lipoprotein; triglycerides

https://doi.org/10.11613/BM.2021.010701

Sample size, power and effect size revisited: simplified and practical approaches in pre-clinical, clinical and laboratory studies

Ceyhan Ceran Serdar, Murat Cihan, Doğan Yücel, Muhittin A Serdar

Review, Volume 31, Articles ahead of print

KEYWORDS: biostatistics; effect size; power analysis; sample size

https://doi.org/10.11613/BM.2021.010502

Estimation of the measurement uncertainty and practical suggestion for the description of the metrological traceability in clinical laboratories

Raúl Rigo-Bonnin, Noelia Díaz-Troyano, Laura García-Tejada, Albert Marcè-Galindo, Míriam Valbuena-Asensio, Francesca Canalias

Review, Volume 31, Articles ahead of print

KEYWORDS: biostatistics; quality control; standardization; traceability; uncertainty

https://doi.org/10.11613/BM.2021.010501

Poem: Waiting for the barbarian Corona viruses

Eleftherios P. Diamandis

Letter to the editor, Volume 31, Articles ahead of print

https://doi.org/10.11613/BM.2021.010401

Evaluation of articles in metabolism research on the basis of their citations

Yi Xiang Zhan, D’arcy Turner, Daniela Tritz, Kelly Natarajan, Mo Som, Matt Vassar

Research Integrity Corner, Volume 31, Articles ahead of print

KEYWORDS: metabolism; research waste; Scopus; citation; bibliometrics

https://doi.org/10.11613/BM.2021.010201

31st Symposium Croatian Society of Medical Biochemistry and Laboratory Medicine: Haemodialysis - clinical and diagnostic challenges

Symposium abstracts, Volume 30, October, Issue 3

Comparison of a rapid immunochromatographic test with a chemiluminescence immunoassay for detection of anti-SARS-CoV-2 IgM and IgG

Caterina Maria Gambino, Bruna Lo Sasso, Claudia Colomba, Rosaria Vincenza Giglio, Luisa Agnello, Giulia Bivona, Marcello Ciaccio

Short communication, Volume 30, October, Issue 3

KEYWORDS: COVID-19; serological test; antibodies; CLIA; immunochromatography

https://doi.org/10.11613/BM.2020.030901

A rare case of tuberculosis-induced hypercalcemia

Loris Wauthier, Xavier Theunssens, Patrick Durez, Catherine Fillée, Diane Maisin, Damien Gruson

Case report, Volume 30, October, Issue 3

KEYWORDS: hypercalcemia; tuberculosis; rheumatoid polyarthritis; calcitriol

https://doi.org/10.11613/BM.2020.030801

Urine neutrophil gelatinase-associated lipocalin concentration in healthy newborns during the first three postnatal days

Vinka Mikulić, Dunja Rogić, Ivanka Mikulić, Kristina Ljubić, Ana Ćuk, Vajdana Tomić, Helena Radić Mišković

Original Articles, Volume 30, October, Issue 3

KEYWORDS: neutrophil gelatinase-associated lipocalin; urine; healthy term newborns

https://doi.org/10.11613/BM.2020.030706

Verification of automated latex-enhanced particle immunoturbidimetric D-Dimer assays on different analytical platforms and comparability of test results

Ivana Lapić, Désirée Coen Herak, Snježana Prpić, Andrea Prce, Vanja Raščanec, Renata Zadro, Dunja Rogić

Original Articles, Volume 30, October, Issue 3

KEYWORDS: haemostasis; blood coagulation tests; D-Dimer; immunoturbidimetry; validation study

https://doi.org/10.11613/BM.2020.030705

Test results comparison and sample stability study: is the BD Barricor tube a suitable replacement for the BD RST tube?

Sanja Mandić, Dario Mandić, Iva Lukić, Tara Rolić, Vesna Horvat, Maja Lukić, Silvija Osvald, Vatroslav Šerić

Original Articles, Volume 30, October, Issue 3

KEYWORDS: BD Barricor tube; stability; serum; plasma; evaluation

https://doi.org/10.11613/BM.2020.030704

Analysis of serum homocysteine in the laboratory practice - comparison of the direct chemiluminescence immunoassay and high performance liquid chromatography coupled with fluorescent detection

Łukasz Paprotny, Dorota Wianowska, Magdalena Izdebska, Agnieszka Celejewska, Dorota Szewczak, Janusz Solski

Original Articles, Volume 30, October, Issue 3

KEYWORDS: homocysteine; immunoassay; luminescent measurements; liquid chromatography

https://doi.org/10.11613/BM.2020.030703

A method comparison study of a point-of-care blood gas analyser with a laboratory auto-analyser for the determination of potassium concentrations during hyperkalaemia in patients with kidney disease

Mogamat-Yazied Chothia, Patricia Kassum, Annalise Zemlin

Original Articles, Volume 30, October, Issue 3

KEYWORDS: point-of-care; emergency department; potassium concentrations; hyperkalaemia

https://doi.org/10.11613/BM.2020.030702

Analytical bias of automated immunoassays for six serum steroid hormones assessed by LC-MS/MS

Željko Debeljak, Ivana Marković, Jasna Pavela, Iva Lukić, Dario Mandić, Sanja Mandić, Vesna Horvat, Vatroslav Šerić

Original Articles, Volume 30, October, Issue 3

KEYWORDS: steroid hormone; immunoassay; bias; LC-MS/MS; method comparison

https://doi.org/10.11613/BM.2020.030701

Potential of modern circulating cell-free DNA diagnostic tools for detection of specific tumour cells in clinical practice

Jernej Gašperšič, Alja Videtič Paska

Review, Volume 30, October, Issue 3

KEYWORDS: cfDNA; NGS; personalized medicine; liquid biopsy; ctDNA

https://doi.org/10.11613/BM.2020.030504

SARS-CoV-2 – a new challenge for laboratory medicine

Slavica Dodig, Ivana Čepelak, Daniela Čepelak Dodig, Renata Laškaj

Review, Volume 30, October, Issue 3

KEYWORDS: biomarkers; COVID-19; SARS-CoV-2; laboratory medicine; patient safety

https://doi.org/10.11613/BM.2020.030503

Inflammatory and angiogenic biomarkers in diabetic retinopathy

Snježana Kaštelan, Ivana Orešković, Filip Bišćan, Helena Kaštelan, Antonela Gverović Antunica

Review, Volume 30, October, Issue 3

KEYWORDS: diabetic retinopathy; biomarkers; inflammation; angiogenesis

https://doi.org/10.11613/BM.2020.030502

Laboratory testing of extravascular body fluids: National recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Part II – Synovial fluid

Anja Jokic, Lara Milevoj Kopcinovic, Jelena Culej, Irena Kocijan, Marija Bozovic

Review, Volume 30, October, Issue 3

KEYWORDS: recommendations; synovial fluid; crystal analysis; osteoarthritis; gout

https://doi.org/10.11613/BM.2020.030501

Experience on how to implement a preanalytical and POCT unit in Madrid’s IFEMA field hospital during this unprecedented COVID-19 emergency

Jorge Díaz–Garzón, Paloma Oliver, Gema Crespo, Marta Duque, Pilar Fernandez-Calle, Marta Gómez, Roberto Mora, Isabel Moreno, Lydia Pascual, Ana-Laila Qasem, Olaia Rodriguez-Fraga, Manuela Simón, Antonio Buño

Letter to the editor, Volume 30, October, Issue 3

KEYWORDS: COVID-19; field hospital; laboratory organization and management; preanalytics; POCT

https://doi.org/10.11613/BM.2020.030403

Laboratory markers included in the Corona Score can identify false negative results on COVID-19 RT-PCR in the emergency room

Roberto Assandri, Ciro Canetta, Giovanni Viganò, Elisabetta Buscarini, Alessandro Scartabellati, Alessandro Montanelli

Letter to the editor, Volume 30, October, Issue 3

KEYWORDS: COVID-19; Emergency room; RT-PCR; laboratory markers; Corona score

https://doi.org/10.11613/BM.2020.030402

Rate of re-positive RT-PCR test among patients recovered from COVID-19

Parham Habibzadeh, Mohammad M. Sajadi, Amir Emami, Mohammad Hossein Karimi, Mahboobeh Yadollahie, Maryam Kucheki, Sahar Akbarpoor, Farrokh Habibzadeh

Letter to the editor, Volume 30, October, Issue 3

KEYWORDS: COVID-19; RT-PCR; laboratory test

https://doi.org/10.11613/BM.2020.030401

Before and after enforcement of GDPR: Personal data protection requests received by Croatian Personal Data Protection Agency from academic and research institutions

Livia Puljak, Anamarija Mladinić, Ron Iphofen, Zvonimir Koporc

Research integrity corner, Volume 30, October, Issue 3

KEYWORDS: data protection; scientific research; European data protection board; general data protection regulation

https://doi.org/10.11613/BM.2020.030201

Corrigendum to: Preanalytical issues related to routine and diagnostic glucose tests: Results from a survey in Spain

Isabel García-del-Pino, Josep M. Bauça, Carolina Gómez, Andrea Caballero, María Antonia Llopis, Mercedes Ibarz, Débora Martínez, Montserrat Ventura, Itziar Marzana, Juan J. Puente, Marta Segovia, Paloma Salas, Rubén Gómez-Rioja

Corrigendum, Volume 30, June, Issue 2

https://doi.org/10.11613/BM.2020.021201

A case of severe pseudohyperkalaemia due to muscle contraction

Jan Van Elslande, Toon Dominicus, Jaan Toelen, Glynis Frans, Pieter Vermeersch

Preanalytical Mysteries, Volume 30, June, Issue 2

KEYWORDS: hyperkalaemia; pseudohyperkalaemia; preanalytical phase; case report

https://doi.org/10.11613/BM.2020.021004

Case report of a phantom pheochromocytoma

Caroline M Joyce, Audrey Melvin, Paula M O’Shea, Seán J Costelloe, Domhnall J O’Halloran

Preanalytical Mysteries, Volume 30, June, Issue 2

KEYWORDS: case report; pheochromocytoma; metanephrines; false positive; sulfasalazine

https://doi.org/10.11613/BM.2020.021003

Dark brown serum and plasma samples: a case report

Lora Dukic, Nikolina Maric, Ana-Maria Simundic

Preanalytical mysteries, Volume 30, June, Issue 2

KEYWORDS: case report; critical care; extra-analytical phase; sample coloration

https://doi.org/10.11613/BM.2020.021002

Case report of spuriously low sodium and calcium in a 36-year-old male in primary care

Seán J. Costelloe, Kelly McCarthy, Marguerite O’Connell, Mark Butler

Preanalytical mysteries, Volume 30, June, Issue 2

KEYWORDS: delayed separation; spurious hyponatraemia; spurious hypocalcaemia; haemolysis; case report

https://doi.org/10.11613/BM.2020.021001

Verification of the Canadian Laboratory Initiative on Paediatric Reference Intervals (CALIPER) reference values in Croatian children and adolescents

Renata Zrinski Topić, Jasna Leniček Krleža

Original Articles, Volume 30, June, Issue 2

KEYWORDS: hormone; immunoassay; paediatric; reference value

https://doi.org/10.11613/BM.2020.020710

Patient-based quality control for glucometers: using the moving sum of positive patient results and moving average

Chun Yee Lim, Tony Badrick, Tze Ping Loh

Original Articles, Volume 30, June, Issue 2

KEYWORDS: laboratory management; quality control; moving average; moving sum of positive patient results; patient-based quality control

https://doi.org/10.11613/BM.2020.020709

Quality improvement project: Reducing non-conformities of the samples for haemostasis testing in a secondary healthcare centre through the nurses’ education in phlebotomy

Patricija Banković Radovanović

Original Articles, Volume 30, June, Issue 2

KEYWORDS: quality improvement; phlebotomy; education; pre-analytical phase

https://doi.org/10.11613/BM.2020.020708

The results of external quality assessment programme on urine leukocyte and erythrocyte counting in Poland

Agnieszka Ćwiklińska, Robert Kowalski, Barbara Kortas-Stempak, Agnieszka Kuchta, Aleksandra Fijałkowska, Gabriela Bednarczuk, Maciej Jankowski

Original Articles, Volume 30, June, Issue 2

KEYWORDS: erythrocytes; leukocytes; quality control; standardisation; urine

https://doi.org/10.11613/BM.2020.020707

Survey on request form content and result reporting in therapeutic drug monitoring service among laboratories in Czechia and Slovakia

Tomáš Šálek, Petr Schneiderka, Barbora Studená, Michaela Votroubková

Original Articles, Volume 30, June, Issue 2

KEYWORDS: drug monitoring; pharmacokinetics; preanalytical phase; clinical laboratory services; kidney function tests

https://doi.org/10.11613/BM.2020.020706

Simple thrombin-based method for eliminating fibrinogen interference in serum protein electrophoresis of haemodialysed patients

Anamarija Rade, Anamarija Đuras, Irena Kocijan, Patricija Banković Radovanović, Ana Turčić

Original papers, Volume 30, June, Issue 2

KEYWORDS: fibrinogen; electrophoresis; central venous catheter; thrombin; interference

https://doi.org/10.11613/BM.2020.020705

Changes in error rates in the Australian key incident monitoring and management system program

Stephanie Gay, Tony Badrick

Original papers, Volume 30, June, Issue 2

KEYWORDS: preanalytical errors; postanalytical errors; preanalytical risk; postanalytical risk

https://doi.org/10.11613/BM.2020.020704

Analytical performance assessment and improvement by means of the Failure mode and effect analysis (FMEA)

Leonor Guiñón, Anna Soler, Mónica Gisell Díaz, Rosa María Fernández, Nayra Rico, Josep Lluís Bedini, Aurea Mira, Luisa Alvarez

Original papers, Volume 30, June, Issue 2

KEYWORDS: risk management; FMEA; sigma metric; analytical performance; quality control

https://doi.org/10.11613/BM.2020.020703

General position of Croatian medical biochemistry laboratories on autovalidation: survey of the Working Group for Post-analytics of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Vladimira Rimac, Anja Jokic, Sonja Podolar, Jelena Vlasic Tanaskovic, Lorena Honovic, Jasna Lenicek Krleza

Original papers, Volume 30, June, Issue 2

KEYWORDS: postanalytical phase; autovalidation; clinical laboratory; questionnaire

https://doi.org/10.11613/BM.2020.020702

Long-term stability of clinically relevant chemistry analytes in pleural and peritoneal fluid

Lara Milevoj Kopcinovic, Marija Brcic, Alen Vrtaric, Adriana Unic, Marija Bozovic, Nora Nikolac Gabaj, Marijana Miler, Jelena Culej

Original papers, Volume 30, June, Issue 2

KEYWORDS: stability; pleural effusion; peritoneal effusion; preanalytical phase

https://doi.org/10.11613/BM.2020.020701

Errors within the total laboratory testing process, from test selection to medical decision-making – A review of causes, consequences, surveillance and solutions

Cornelia Mrazek, Giuseppe Lippi, Martin H Keppel, Thomas K Felder, Hannes Oberkofler, Elisabeth Haschke-Becher, Janne Cadamuro

Review, Volume 30, June, Issue 2

KEYWORDS: total testing process; extra-analytical phase; quality indicators; laboratory medicine; patient safety

https://doi.org/10.11613/BM.2020.020502

In sickness and in health: pivotal role of vitamin D

Nora Nikolac Gabaj, Adriana Unic, Marijana Miler, Tomislav Pavicic, Jelena Culej, Ivan Bolanca, Davorka Herman Mahecic, Lara Milevoj Kopcinovic, Alen Vrtaric

Review, Volume 30, June, Issue 2

KEYWORDS: vitamin D; preanalytical variability; diabetes mellitus; polymorphism; fertility; extravascular body fluids

https://doi.org/10.11613/BM.2020.020501

Copyright violation of predators in scientific publishing - Biochemia Medica’s harmful experience and proposed solution

Daria Pašalić, Vesna Šupak Smolčić

Research integrity corner - editorial, Volume 30, June, Issue 2

KEYWORDS: copyright violation; cybercriminal; predatory journal

https://doi.org/10.11613/BM.2020.020201

The top-down approach to measurement uncertainty: which formula should we use in laboratory medicine?

Flávia Martinello, Nada Snoj, Milan Skitek, Aleš Jerin

Lessons in biostatistics, Volume 30, June, Issue 2

KEYWORDS: measurement uncertainty; bias; uncertainty; total error; quality control

https://doi.org/10.11613/BM.2020.020101

The effect of jet-lag on serum concentrations of thyroid stimulating hormone and prolactin: A case report

Merve Sibel Gungoren, Deniz Ilhan Topcu, Cevdet Zungun

Preanalytical Mysteries, Volume 30, February, Issue 1

KEYWORDS: preanalytical phase; case report; jet-lag; thyroid stimulating hormone; prolactin

https://doi.org/10.11613/BM.2020.011003

Unexpected abnormal coagulation test results in a 2-year-old child: A case report

Patricija Banković Radovanović, Tanja Živković Mikulčić, Jasmina Simović Medica

Preanalytical Mysteries, Volume 30, February, Issue 1

KEYWORDS: case report; preanalytical phase; sample collection; coagulation

https://doi.org/10.11613/BM.2020.011002

High anion gap metabolic acidosis caused by D-lactate: mind the time of blood collection

Matthias Weemaes, Martin Hiele, Pieter Vermeersch

Preanalytical Mysteries, Volume 30, February, Issue 1

KEYWORDS: D-lactate; D-lactic acidosis; high anion gap acidosis; preanalytical phase; case report

https://doi.org/10.11613/BM.2020.011001

Six Sigma revisited: We need evidence to include a 1.5 SD shift in the extraanalytical phase of the total testing process

Abdurrahman Coskun, Cristiano Ialongo

Short Communication, Volume 30, February, Issue 1

KEYWORDS: extraanalytical phase; shift; Sigma metric; Six Sigma; total testing process

https://doi.org/10.11613/BM.2020.010901

An unconscious man with profound drug-induced hypoglycaemia

Toon Schiemsky, Guy Vundelinckx, Kathleen Croes, Joris Penders, Koen Desmet, Steven Pauwels, Pieter Vermeersch

Case Reports, Volume 30, February, Issue 1

KEYWORDS: hypoglycaemia; tramadol; insulin; poisoning

https://doi.org/10.11613/BM.2020.010802

A case of IgE myeloma transformed into IgE-producing plasma cell leukaemia

Nicolas Galakhoff, Cyril Leven, Jean-Richard Eveillard, Adrian Tempescul, Hélène Kerspern, Cécile Aubron, Caroline Buors, Éric Lippert, Jean-Luc Carré, Maël Padelli

Case Reports, Volume 30, February, Issue 1

KEYWORDS: immunofixation; immunoglobulin E; monoclonal gammopathy of undetermined significance; multiple myeloma; plasma cell leukaemia

https://doi.org/10.11613/BM.2020.010801

Title does matter: a cross-sectional study of 30 journals in the Medical Laboratory Technology category

Marina Njire Braticevic, Ivana Babic, Irena Abramovic, Anja Jokic, Martina Horvat

Original Articles, Volume 30, February, Issue 1

KEYWORDS: cross-sectional studies; medical laboratory technology; publications; bibliometrics

https://doi.org/10.11613/BM.2020.010708

Test validation, method comparison and reference range for the measurement of β-hydroxybutyrate in peripheral blood samples

Frank Bernhard Kraus, Marija Kocijancic, Alexander Kluttig, Beatrice Ludwig-Kraus

Original Articles, Volume 30, February, Issue 1

KEYWORDS: β-hydroxybutyrate; ketoacidosis; method validation; reference range; urine ketones

https://doi.org/10.11613/BM.2020.010707

Analytical verification and comparison of chromogenic assays for dabigatran, rivaroxaban and apixaban determination on BCSXP and STA Compact Max analysers

Ivana Ćelap, Sandra Margetić, Marija Brčić, Roman Mihić

Original Articles, Volume 30, February, Issue 1

KEYWORDS: chromogenic assay; dabigatran; rivaroxaban; apixaban; method comparison

https://doi.org/10.11613/BM.2020.010706

Knowledge and awareness of iodine intake - survey among Croatian women of reproductive age

Valentina Vidranski, Anita Radman, Katarina Kajić, Ana Bronić

Original Articles, Volume 30, February, Issue 1

KEYWORDS: fertility; iodine; knowledge; survey; thyroid diseases

https://doi.org/10.11613/BM.2020.010705

Preanalytical issues related to routine and diagnostic glucose tests: Results from a survey in Spain

Isabel García-del-Pino, Josep M. Bauça, Carolina Gómez, Andrea Caballero, María Antonia Llopis, Mercedes Ibarz, Débora Martínez, Montserrat Ventura, Itziar Marzana, Juan J. Puente, Marta Segovia, Paloma Salas, Rubén Gómez-Rioja

Original Articles, Volume 30, February, Issue 1

KEYWORDS: glucose; preanalytical phase; glycolysis; diabetes mellitus; survey

https://doi.org/10.11613/BM.2020.010704

Study of the preanalytical variables affecting the measurement of clinically relevant free-circulating microRNAs: focus on sample matrix, platelet depletion, and storage conditions

Martina Faraldi, Veronica Sansoni, Silvia Perego, Marta Gomarasca, Jakub Kortas, Ewa Ziemann, Giuseppe Banfi, Giovanni Lombardi

Original Articles, Volume 30, February, Issue 1

KEYWORDS: circulating microRNA; biomarkers; plasma; preanalytical phase

https://doi.org/10.11613/BM.2020.010703

Chromogenic anti-FXa assay calibrated with low molecular weight heparin in patients treated with rivaroxaban and apixaban: possibilities and limitations

Sandra Margetić, Ivana Ćelap, Diana Delić Brkljačić, Nikola Pavlović, Sandra Šupraha Goreta, Ivana Kobasić, Arijana Lovrenčić-Huzjan, Vanja Bašić Kes

Original Articles, Volume 30, February, Issue 1

KEYWORDS: apixaban; DOAC; factor Xa inhibitors; LMWH; rivaroxaban

https://doi.org/10.11613/BM.2020.010702

Platelet indices in stable chronic obstructive pulmonary disease – association with inflammatory markers, comorbidities and therapy

Iva Hlapčić, Anita Somborac-Bačura, Sanja Popović-Grle, Andrea Vukić Dugac, Dunja Rogić, Ivana Rako, Tihana Žanić Grubišić, Lada Rumora

Original Articles, Volume 30, February, Issue 1

KEYWORDS: chronic obstructive pulmonary disease; inflammation; blood platelets; therapy

https://doi.org/10.11613/BM.2020.010701

Laboratory testing of extravascular body fluids: National recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Part I – Serous fluids

Lara Milevoj Kopcinovic, Jelena Culej, Anja Jokic, Marija Bozovic, Irena Kocijan

Review, Volume 30, February, Issue 1

KEYWORDS: harmonization; pleural effusion; pericardial effusion; ascites

https://doi.org/10.11613/BM.2020.010502

Integrated diagnostics: the future of laboratory medicine?

Giuseppe Lippi, Mario Plebani

Review, Volume 30, February, Issue 1

KEYWORDS: integrated diagnostics; laboratory medicine; pathology; radiology

https://doi.org/10.11613/BM.2020.010501

Statistical distributions commonly used in measurement uncertainty in laboratory medicine

Abdurrahman Coskun, Wytze P. Oosterhuis

Lessons in Biostatistics, Volume 30, February, Issue 1

KEYWORDS: measurement uncertainty; normal distribution; triangular distribution; uniform distribution

https://doi.org/10.11613/BM.2020.010101

Corrigendum to: Assessment of the degree of adherence of medical laboratories to KDIGO 2012 guideline for evaluation and management of CKD in Czechia and Slovakia

Tomáš Šálek, Bedřich Friedecký, Josef Kratochvíla, Květa Pelinková, Marek Budina

Erratum, Volume 29, October, Issue 3

https://doi.org/10.11613/BM.2019.031202

Corrigendum to: Analytical evaluation of the new Seal Autoanalyzer 3 High Resolution for urinary iodine determination

Valentina Vidranski, Maja Franceschi, Dražena Krilić, Tomislav Jukić, Ivan Mihaljević, Zvonko Kusić

Corrigendum, Volume 29, October, Issue 3

https://doi.org/10.11613/BM.2019.031201

30th Symposium Croatian Society of Medical Biochemistry and Laboratory Medicine: Vitamin D in health and disease

Symposium abstracts, Volume 29, October, Issue 3

Flushing of an intravenous catheter: a cause for unreliable laboratory results

Rutger C.C. Hengeveld, Maaike C. Gerards, Bianca E. Olofsen, Milan L. Ridderikhof, Victor F.H.A. Hakkenberg van Gaasbeek, Peter A. Leenhouts, Edmée C. van Dongen-Lases

Preanalytical Mysteries, Volume 29, October, Issue 3

KEYWORDS: preanalytical phase; phlebotomy; intravenous catheter

https://doi.org/10.11613/BM.2019.031001

Escherichia coli spheroplasts in a Croatian patient misclassified by two urine sediment analysers as erythrocytes: case report

Ana Nikler, Vanja Radišić Biljak, Helena Čičak, Nikolina Marić, Danijela Bejuk, Jose Antonio Tesser Poloni, Ana-Maria Simundic

Case Reports, Volume 29, October, Issue 3

KEYWORDS: spheroplasts; bacterial forms; urinalysis; misclassification

https://doi.org/10.11613/BM.2019.030801

Clinician’s opinion about critical risk results proposed by the Croatian Chamber of Medical Biochemists: a survey in one Croatian tertiary hospital

Pavica Šonjić, Ana Nikler, Dora Vuljanić, Lora Dukić, Ana-Maria Šimundić

Original Articles, Volume 29, October, Issue 3

KEYWORDS: critical results; survey; post-analytical phase; laboratory management

https://doi.org/10.11613/BM.2019.030711

Optimizing moving average control procedures for small-volume laboratories: can it be done?

Vera Lukić, Svetlana Ignjatović

Original Articles, Volume 29, October, Issue 3

KEYWORDS: quality control; moving average; bias detection simulation; MA Generator software

https://doi.org/10.11613/BM.2019.030710

Verification study of free light chains assays on reagent-optimized analysers

Dragana Šegulja, Danica Matišić, Karmela Barišić, Dunja Rogić

Original Articles, Volume 29, October, Issue 3

KEYWORDS: M components; serum free light chains; immunoassay; gammopathy; monoclonal

https://doi.org/10.11613/BM.2019.030709

Time-dependent variation of ionized calcium in serum samples

Antonija Perović, Marina Njire Bratičević

Original Articles, Volume 29, October, Issue 3

KEYWORDS: ionized calcium; serum; heparin; specimen handling; pre-analytical phase

https://doi.org/10.11613/BM.2019.030708

Classical pathway activity C3c, C4 and C1-inhibitor protein reference intervals determination in EDTA plasma

Benjamin Lopez, Nicolas Bertier, Emmanuel Ledoult, Romane Joudinaud, Mehdi Maanaoui, Victoria Majerus, Emmanuelle Moitrot, Anne-Sophie Deleplancque, Stéphanie Rogeau, David Launay, Guillaume Lefèvre, Myriam Labalette, Sylvain Dubucquoi

Original Articles, Volume 29, October, Issue 3

KEYWORDS: reference values; complement C3c; complement C4; classical complement pathway; complement C1 inhibitor protein

https://doi.org/10.11613/BM.2019.030707

Rapid serum tube technology overcomes problems associated with use of anticoagulants

Kong-Nan Zhao, Goce Dimeski, John de Jersey, Lambro A Johnson, Michael Grant, Paul P Masci, Martin F Lavin

Original Articles, Volume 29, October, Issue 3

KEYWORDS: prothrombin activators; serum; anticoagulants; analytes

https://doi.org/10.11613/BM.2019.030706

Effectiveness of minimum retesting intervals in managing repetitive laboratory testing: experience from a Croatian university hospital

Ivana Lapić, Dunja Rogić, Mirjana Fuček, Ružica Galović

Original Articles, Volume 29, October, Issue 3

KEYWORDS: evidence-based practice; clinical laboratory services; pre-analytical phase; cost analysis

https://doi.org/10.11613/BM.2019.030705

Assessment of the degree of adherence of medical laboratories to KDIGO 2012 guideline for evaluation and management of CKD in Czechia and Slovakia

Šálek Tomáš, Friedecký Bedřich, Kratochvíla Josef, Pelinková Květa, Budina Marek

Original Articles, Volume 29, October, Issue 3

KEYWORDS: creatinine; cystatin C; glomerular filtration; estimated glomerular filtration rate; post-analytical phase

https://doi.org/10.11613/BM.2019.030704

Assessment of a laboratory critical risk result notification protocol in a tertiary care hospital and their use in clinical decision making

Jose A. Delgado Rodríguez, Maria I. Pastor García, Cristina Gómez Cobo, Antonia R. Pons Más, Isabel Llompart Alabern, Josep Miquel Bauça

Original Articles, Volume 29, October, Issue 3

KEYWORDS: phone notification; turnaround time; clinical decision making; critical risk result

https://doi.org/10.11613/BM.2019.030703

Determining biological variation of serum parathyroid hormone in healthy adults

Müjgan Ercan, Emiş Deniz Akbulut, Esin Avcı, Çiğdem Yücel, Esra Fırat Oğuz, Turan Turhan, Muhittin Serdar

Original Articles, Volume 29, October, Issue 3

KEYWORDS: biological variation; individuality; reference change value; PTH; quality specification

https://doi.org/10.11613/BM.2019.030702

Preanalytical classical and alternative complement pathway activity loss

Koen O.A. Vercauteren, Stijn Lambrecht, Joris Delanghe

Original Articles, Volume 29, October, Issue 3

KEYWORDS: preanalytical phase; alternative and classical complement pathway; complement haemolytic activity assay; complement C3; complement C3d

https://doi.org/10.11613/BM.2019.030701

Hallmarks of senescence and aging

Slavica Dodig, Ivana Čepelak, Ivan Pavić

Review, Volume 29, October, Issue 3

KEYWORDS: senescence; aging; biomarkers; hallmarks

https://doi.org/10.11613/BM.2019.030501

The first step in creating national Chronic Kidney Disease (CKD) guidelines – a questionnaire

Vanja Radišić Biljak, Anders Grubb, Isabel Cachapuz Guerra, Etienne Cavalier, Stella Raymondo, Rosa Sierra-Amor, Michele Mussap, Shanthi Naidu Kamathan, Dogan Yucel, Pradip Datta, Takashi Wada, Flavio F. Alcantara

Editorial, Volume 29, October, Issue 3

KEYWORDS: chronic kidney disease (CKD); International Federation of Clinical Chemistry and Laboratory Medicine (IFCC); guidelines; action plan; questionnaire

https://doi.org/10.11613/BM.2019.030301

Confidence interval of percentiles in skewed distribution: The importance of the actual coverage probability in practical quality applications for laboratory medicine

Cristiano Ialongo

Lessons in Biostatistics, Volume 29, October, Issue 3

KEYWORDS: biostatistics; confidence intervals; statistical data analysis; health care quality indicators

https://doi.org/10.11613/BM.2019.030101

An abrupt rise of coagulation error messages on ACL TOP automated analysers

Bas Calcoen, Koen Desmet, Pieter Vermeersch

Preanalytical Mysteries, Volume 29, June, Issue 2

KEYWORDS: preanalytical phase; blood coagulation test; diagnostic error; blood specimen collection

https://doi.org/10.11613/BM.2019.021002

Description of interference in the measurement of troponin T by a high-sensitivity method

Miguel Aliste-Fernández, Gemma Sole-Enrech, Ruth Cano-Corres, Silvia Teodoro-Marin, Eugenio Berlanga-Escalera

Preanalytical Mysteries, Volume 29, June, Issue 2

KEYWORDS: high-sensitivity troponin T; interference; case report

https://doi.org/10.11613/BM.2019.021001

High-sensitivity cardiac Troponin T delta concentration after repeat pulmonary vein isolation

Ivan Zeljkovic, Sven Knecht, Florian Spies, Tobias Reichlin, Beat Schaer, Stefan Osswald, Michael Kühne, Christian Sticherling

Short communications, Volume 29, June, Issue 2

KEYWORDS: atrial fibrillation; pulmonary vein isolation; high-sensitivity troponin T; repeat procedure; recurrence

https://doi.org/10.11613/BM.2019.020902

Establishing the 99 percentile for high sensitivity cardiac troponin I in healthy blood donors from Southern Italy

Luisa Agnello, Chiara Bellia, Concetta Scazzone, Giulia Bivona, Giorgia Iacolino, Caterina Maria Gambino, Maddalena Muratore, Bruna Lo Sasso, Marcello Ciaccio

Short communications, Volume 29, June, Issue 2

KEYWORDS: troponin I; myocardial infarction; reference values; high sensitivity; 99th percentile

https://doi.org/10.11613/BM.2019.020901

Analytical evaluation of the new Seal Autoanalyzer 3 High Resolution for urinary iodine determination

Valentina Vidranski, Maja Franceschi, Dražena Krilić, Tomislav Jukić, Ivan Mihaljević, Zvonko Kusić

Original Articles, Volume 29, June, Issue 2

KEYWORDS: colorimetry; iodine; method evaluation; urine

https://doi.org/10.11613/BM.2019.020711

Elevated activated partial thromboplastin time-based clot waveform analysis markers have strong positive association with acute venous thromboembolism

Chuen Wen Tan, McVin Hua Heng Cheen, Wan Hui Wong, Ian Qianhuang Wu, Brian Lee Wei Chua, Sahul Hameed Ahamedulla, Lai Heng Lee, Heng Joo Ng

Original Articles, Volume 29, June, Issue 2

KEYWORDS: blood coagulation; activated partial thromboplastin time; thrombophilia; thrombosis; venous thromboembolism

https://doi.org/10.11613/BM.2019.020710

Reporting categories in urine test strip analysis: Croatian survey and call for action

Ana Dojder, Dora Vuljanić, Valentina Špoljarić, Andrea Saračević, Lora Dukić, Jasna Leniček-Krleža, Jelena Vlašić-Tanasković, Ivana Maradin, Ana Grzunov, Ana-Maria Šimundić

Original Articles, Volume 29, June, Issue 2

KEYWORDS: urine; test strips; reporting; harmonization

https://doi.org/10.11613/BM.2018.020709

Effect of temperature and time delay in centrifugation on stability of select biomarkers of nutrition and non-communicable diseases in blood samples

Ransi Ann Abraham, Praween K. Agrawal, Rajib Acharya, Avina Sarna, Sowmya Ramesh, Robert Johnston, Arjan de Wagt, Nizamuddin Khan, Akash Porwal, Sucheta Banerjee Kurundkar, Arvind Pandey, Raghu Pullakhandam, Krishnapillai Madhavan Nair, Geeta Trilok Kumar

Original Articles, Volume 29, June, Issue 2

KEYWORDS: survey; preanalytical conditions; temperature; time delay; centrifugation

https://doi.org/10.11613/BM.2019.020708

Protein Induced by Vitamin K Absence II (PIVKA-II) as a potential serological biomarker in pancreatic cancer: a pilot study

Sara Tartaglione, Irene Pecorella, Serena Rita Zarrillo, Teresa Granato, Valentina Viggiani, Lucia Manganaro, Cinzia Marchese, Antonio Angeloni, Emanuela Anastasi

Original Articles, Volume 29, June, Issue 2

KEYWORDS: pancreatic cancer; PIVKA-II; CA 19-9; CA 242; CEA

https://doi.org/10.11613/BM.2019.020707

Optimizing laboratory defined macroprolactin algorithm

Milica Šostarić, Adriana Bokulić, Domagoj Marijančević, Ivana Zec

Original Articles, Volume 29, June, Issue 2

KEYWORDS: prolactin; hyperprolactinaemia; macroprolactin; polyethylene glycol

https://doi.org/10.11613/BM.2019.020706

European survey on preanalytical sample handling – Part 2: Practices of European laboratories on monitoring and processing haemolytic, icteric and lipemic samples. On behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE)

Janne Cadamuro, Giuseppe Lippi, Alexander von Meyer, Mercedes Ibarz, Edmee van Dongen, Michael Cornes, Mads Nybo, Pieter Vermeersch, Kjell Grankvist, Joao Tiago Guimaraes, Gunn B.B. Kristensen, Barbara de la Salle, Ana-Maria Simundic

Original Articles, Volume 29, June, Issue 2

KEYWORDS: preanalytics; standardization; survey

https://doi.org/10.11613/BM.2019.020705

European survey on preanalytical sample handling – Part 1: How do European laboratories monitor the preanalytical phase? On behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE)

Janne Cadamuro, Giuseppe Lippi, Alexander von Meyer, Mercedes Ibarz, Edmee van Dongen, Michael Cornes, Mads Nybo, Pieter Vermeersch, Kjell Grankvist, Joao Tiago Guimaraes, Gunn B.B. Kristensen, Barbara de la Salle, Ana-Maria Simundic

Original Articles, Volume 29, June, Issue 2

KEYWORDS: preanalytics; standardization; survey

https://doi.org/10.11613/BM.2019.020704

Haemolysis and lipemia interfere with resistin and myeloperoxidase BioVendor ELISA assays

Andrea Saracevic, Lora Dukic, Ana-Maria Simundic

Original articles, Volume 29, June, Issue 2

KEYWORDS: haemolysis; lipemia; interferences; resistin; myeloperoxidase

https://doi.org/10.11613/BM.2019.020703

Impact of an Andean breakfast on biochemistry and immunochemistry laboratory tests: an evaluation on behalf COLABIOCLI WG-PRE-LATAM

Wilson Bajaña, Eduardo Aranda, Maria Elena Arredondo, Lorena Michele Brennan-Bourdon, Marise Danielle Campelo, Edgar Espinoza, Silvia Flores, Patricia Ochoa, Veronica Vega, Beatriz Varela, Gabriel Lima-Oliveira

Original articles, Volume 29, June, Issue 2

KEYWORDS: blood specimen collection; diagnostic errors; fasting; postprandial period; reproducibility of results

https://doi.org/10.11613/BM.2019.020702

Evaluation of a commercial liquid-chromatography high-resolution mass-spectrometry method for the determination of hepcidin-25

Dietmar Enko, Sieglinde Zelzer, Günter Fauler, Markus Herrmann

Original articles, Volume 29, June, Issue 2

KEYWORDS: hepcidin-25; preanalytical phase; protein biomarker; liquid-chromatography high-resolution mass-spectrometry

https://doi.org/10.11613/BM.2019.020701

A balanced scorecard for assessing a strategic plan in a clinical laboratory

Luisa Alvarez, Anna Soler, Leonor Guiñón, Aurea Mira

Short review, Volume 29, June, Issue 2

KEYWORDS: balanced scorecard; clinical laboratory; management; strategic plan

https://doi.org/10.11613/BM.2019.020601

Croatian Society of Medical Biochemistry and Laboratory Medicine: National recommendations for blood collection, processing, performance and reporting of results for coagulation screening assays prothrombin time, activated partial thromboplastin time, thrombin time, fibrinogen and D-dimer

Ana Bronić, Desiree Coen Herak, Sandra Margetić, Marija Milić

Review, Volume 29, June, Issue 2

KEYWORDS: blood coagulation tests; haemostasis; standardization; harmonization; guidelines

https://doi.org/10.11613/BM.2019.020503

Post-analytical laboratory work: national recommendations from the Working Group for Post-analytics on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Jasna Lenicek Krleza, Lorena Honovic, Jelena Vlasic Tanaskovic, Sonja Podolar, Vladimira Rimac, Anja Jokic

Review, Volume 29, June, Issue 2

KEYWORDS: recommendations; post-analytical phase; clinical laboratory; harmonization; test report

https://doi.org/10.11613/BM.2019.020502

Filaggrin and atopic march

Ivana Čepelak, Slavica Dodig, Ivan Pavić

Review, Volume 29, June, Issue 2

KEYWORDS: atopic dermatitis; atopic diseases; filaggrin

https://doi.org/10.11613/BM.2019.020501

Ethics assessment in research proposals adopting CRISPR technology

Francois Hirsch, Ron Iphofen, Zvonimir Koporc

Research integrity corner, Volume 29, June, Issue 2

KEYWORDS: CRISPR/Cas9; genome editing; ethical review

https://doi.org/10.11613/BM.2019.020202

Rewarding the quantity of peer review could harm biomedical research

Aceil Al-Khatib, Jaime A. Teixeira da Silva

Research integrity corner, Volume 29, June, Issue 2

KEYWORDS: autonomy; biomedical research; ethics in publishing; responsible peer review; scientific misconduct

https://doi.org/10.11613/BM.2019.020201

The likelihood ratio and its graphical representation

Farrokh Habibzadeh, Parham Habibzadeh

Lessons in biostatistics, Volume 29, June, Issue 2

KEYWORDS: ROC curve; diagnostic tests; likelihood ratio

https://doi.org/10.11613/BM.2019.020101

A paradigmatic case of haemolysis and pseudohyperkalemia in blood gas analysis

Gian Luca Salvagno, Davide Demonte, Giuseppe Lippi

Preanalytical Mysteries, Volume 29, February, Issue 1

KEYWORDS: potassium; hyperkalemia; preanalytical variability; diagnostic errors

https://doi.org/10.11613/BM.2019.011003

Case report: An index of suspicion in hyponatraemia

Marizna Barkhuizen, Mariza Hoffmann, Ekkehard WA Zöllner, Rajiv T. Erasmus, Annalise E. Zemlin

Preanalytical Mysteries, Volume 29, February, Issue 1

KEYWORDS: pseudohyponatraemia; electrolyte exclusion effect; case report; serum indices; endogenous interference

https://doi.org/10.11613/BM.2019.011002

Falsely prolonged activated partial thromboplastin time – a pre- and post-analytical issue

Charlotte Gils, Pernille Just Vinholt, Mads Nybo

Preanalytical Mysteries, Volume 29, February, Issue 1

KEYWORDS: activated partial thromboplastin time; haemolysis; lipemia; post-analytical errors; pre-analytical errors

https://doi.org/10.11613/BM.2019.011001

Plasma free DNA: Evaluation of temperature-associated storage effects observed for Roche Cell-Free DNA collection tubes

Dietmar Enko, Gabriele Halwachs-Baumann, Gernot Kriegshäuser

Short Communications, Volume 29, February, Issue 1

KEYWORDS: cell-free nucleic acids; pre-analytical phase; quality improvement

https://doi.org/10.11613/BM.2019.010904

Mistaken assumptions drive new Six Sigma model off the road

Sten Westgard, Hassan Bayat, James O Westgard

Short Communications, Volume 29, February, Issue 1

KEYWORDS: Sigma metrics; Six Sigma; allowable total error

https://doi.org/10.11613/BM.2019.010903

Sigma metric revisited: True known mistakes

Abdurrahman Coskun, Mustafa Serteser, Ibrahim Ünsal

Short Communications, Volume 29, February, Issue 1

KEYWORDS: laboratory error; normal distribution; sigma metric; Six Sigma; uniform distribution

https://doi.org/10.11613/BM.2019.010902

Effects of different anticoagulants on glycated albumin quantification

Graziella Bonetti, Nicola Di Gaetano, Renata Paleari, Ferruccio Ceriotti

Short Communications, Volume 29, February, Issue 1

KEYWORDS: preanalytical phase; serum albumin; diabetes mellitus; anticoagulants

https://doi.org/10.11613/BM.2019.010901

Improving home haemodialysis: Stability evaluation of routine clinical chemistry analytes in blood samples of haemodialysis patients

Lourens J.P. Nonkes, Maaike K. van Gelder, Hans Kemperman, Alferso C. Abrahams, Frans T.J. Boereboom, Maarten J. ten Berg, Karin G.F. Gerritsen

Original Articles, Volume 29, February, Issue 1

KEYWORDS: haemodialysis; clinical chemistry tests; bicarbonates; blood specimen collection

https://doi.org/10.11613/BM.2019.010709

Analytical verification of 12 most commonly used urine dipsticks in Croatia: comparability, repeatability and accuracy

Dora Vuljanić, Ana Dojder, Valentina Špoljarić, Andrea Saračević, Lora Dukić, Jasna Leniček-Krleža, Jelena Vlašić-Tanasković, Ivana Maradin, Ana Grzunov, Željka Vogrinc, Ana-Maria Šimundić

Original Articles, Volume 29, February, Issue 1

KEYWORDS: verification; urine dipsticks; comparability; accuracy; repeatability

https://doi.org/10.11613/BM.2019.010708

Faecal calprotectin determination: impact of preanalytical sample treatment and stool consistency on within- and between-method variability

Gordana Juricic, Tina Brencic, Andrea Tesija-Kuna, Milena Njegovan, Lorena Honovic

Original Articles, Volume 29, February, Issue 1

KEYWORDS: calprotectin; preanalytical phase; inflammatory bowel disease; immunoassay

https://doi.org/10.11613/BM.2019.010707

Changes of salivary biomarkers under different storage conditions: effects of temperature and length of storage

Tomás Barranco, Camila P Rubio, Asta Tvarijonaviciute, Mónica Rubio, Elena Damia, Elsa Lamy, Ramón Cugat, José J Cerón, Fernando Tecles, Damián Escribano

Original Articles, Volume 29, February, Issue 1

KEYWORDS: biomarker; enzyme stability; oxidative stress; saliva; temperature

https://doi.org/10.11613/BM.2019.010706

Higher serum lectin-like oxidized low-density lipoprotein receptor-1 in patients with stable coronary artery disease is associated with major adverse cardiovascular events: A multicentre pilot study

Zi-wen Zhao, Yi-wei Xu, Shu-mei Li, Jin-jian Guo, Tao Yi, Liang-long Chen

Original Articles, Volume 29, February, Issue 1

KEYWORDS: coronary artery disease; sLOX-1; prognosis; major adverse cardiovascular events; biomarker

https://doi.org/10.11613/BM.2019.010705

Analysis of laboratory critical values at a referral Spanish tertiary university hospital

Ariadna Arbiol-Roca, Sofía Corral-Comesaña, Ruth Cano-Corres, María José Castro-Castro, Macarena Dastis-Arias, Dolors Dot-Bach

Original Articles, Volume 29, February, Issue 1

KEYWORDS: critical values limits; critical values notification; patient safety

https://doi.org/10.11613/BM.2019.010704

Fast skeletal troponin I, but not the slow isoform, is increased in patients under statin therapy: a pilot study

Alessandro Trentini, Savino Spadaro, Valentina Rosta, Maria C Manfrinato, Carlo Cervellati, Francesca Dalla Corte, Stefania Hanau, Carlo A Volta, Tiziana Bellini

Original Articles, Volume 29, February, Issue 1

KEYWORDS: statin; fast skeletal troponin; slow skeletal troponin; muscle damage; creatine kinase

https://doi.org/10.11613/BM.2019.010703

Prognostic value of procalcitonin and lipopolysaccharide binding protein in cancer patients with chemotherapy-associated febrile neutropenia presenting to an emergency department

Luis García de Guadiana-Romualdo, Pablo Cerezuela-Fuentes, Ignacio Español-Morales, Patricia Esteban-Torrella, Enrique Jiménez-Santos, Ana Hernando-Holgado, María Dolores Albaladejo-Otón

Original Articles, Volume 29, February, Issue 1

KEYWORDS: febrile neutropenia; prognosis; Multinational Association for Supportive Care in Cancer; procalcitonin; lipopolysaccharide binding protein

https://doi.org/10.11613/BM.2019.010702

Standardization in laboratory medicine: Two years’ experience from category 1 EQA programs in Spain

Carmen Ricós, Carmen Perich, Beatriz Boned, Elisabet González-Lao, Jorge Diaz-Garzón, Montserrat Ventura, Sandra Bullich, Zoraida Corte, Joana Minchinela, Fernando Marques, Margarita Simón, Virtudes Alvarez, José-Vicente García-Lario, Pilar Fernández-Fern

Original Articles, Volume 29, February, Issue 1

KEYWORDS: standardization; external quality assessment; traceability; bias

https://doi.org/10.11613/BM.2019.010701

A review of urinary angiotensin converting enzyme 2 in diabetes and diabetic nephropathy

Akankwasa Gilbert, Jianhua Liu, Guixue Cheng, Changjuan An, Kabuye Deo, Abalinda Mary Gorret, Xiaosong Qin

Review, Volume 29, February, Issue 1

KEYWORDS: angiotensin converting enzyme; diabetic nephropathy; mRNA

https://doi.org/10.11613/BM.2019.010501

Correcting duplicate publications: follow up study of MEDLINE tagged duplications

Mario Malički, Ana Utrobičić, Ana Marušić

Research Integrity Corner, Volume 29, February, Issue 1

KEYWORDS: duplicate publication; retraction of publication; authorship; scientific misconduct; published erratum

https://doi.org/10.11613/BM.2019.010201

Confidence interval for quantiles and percentiles

Cristiano Ialongo

Lessons in Biostatistics, Volume 29, February, Issue 1

KEYWORDS: biostatistics; statistical methods; confidence intervals; extra-analytical phase

https://doi.org/10.11613/BM.2019.010101

9th Congress of the Croatian Society of Medical Biochemistry and Laboratory Medicine with international participation

Symposium abstracts, Volume 28, May, Suppl1

29th Symposium of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Symposium abstracts, Volume 28, October, Issue 3

Effect of cold agglutinins on red blood cell parameters in a trauma patient: a case report

Anita Topic, Lara Milevoj Kopcinovic, Ana Bronic, Marina Pavic

Preanalytical mysteries, Volume 28, October, Issue 3

KEYWORDS: cold agglutinins; preanalytical errors; red blood cell count; spurious complete blood count results

https://doi.org/10.11613/BM.2018.031001

Biotin and high-sensitivity cardiac troponin T assay

Aurélien Schrapp, François Fraissinet, Charles Hervouet, Hélène Girot, Valéry Brunel

Short Communication, Volume 28, October, Issue 3

KEYWORDS: troponin T; biotin; multiple sclerosis; preanalytical phase

https://doi.org/10.11613/BM.2018.030901

Metabolic follow-up of a Croatian patient with gyrate atrophy and a new mutation in the gene: a case report

Marija Zekušić, Ana Škaričić, Ksenija Fumić, Dunja Rogić, Tamara Žigman, Danijela Petković Ramadža, Nenad Vukojević, Véronique Rüfenacht, Valentina Uroić, Ivo Barić

Case Report, Volume 28, October, Issue 3

KEYWORDS: ornithinemia; amino acids; tandem mass spectrometry

https://doi.org/10.11613/BM.2018.030801

Significance of LDL and HDL subclasses characterization in the assessment of risk for colorectal cancer development

Milica Stevanovic, Jelena Vekic, Natasa Bogavac-Stanojevic, Jelena Janac, Zeljka Stjepanovic, Dejan Zeljkovic, Bratislav Trifunovic, Vesna Spasojevic-Kalimanovska, Aleksandra Zeljkovic

Original Papers, Volume 28, October, Issue 3

KEYWORDS: colorectal cancer; risk prediction; lipoprotein subclasses; lipoprotein size; cost-effectiveness

https://doi.org/10.11613/BM.2018.030713

The diagnostic accuracy of clinical and laboratory parameters in the diagnosis of acute appendicitis in the adult emergency department population - a case control pilot study

Ivo Soldo, Vanja Radisic Biljak, Branko Bakula, Maja Bakula, Ana-Maria Simundic

Original Papers, Volume 28, October, Issue 3

KEYWORDS: appendicitis; emergency service; white blood cell count; C-reactive protein; urinalysis

https://doi.org/10.11613/BM.2018.030712

A collaborative study by the Working Group on Hemostasis and Thrombosis of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC) on the interference of haemolysis on five routine blood coagulation tests by evaluation of 269

Chiara Novelli, Matteo Vidali, Bruno Brando, Benedetto Morelli, Giovanna Andreani, Marina Arini, Paola Calzoni, Roberta Giacomello, Barbara Montaruli, Emanuela Muccini, Angela Papa, Paola Pradella, Lucia Ruocco, Fosca Siviero, Filomena Gemma Viola, Mario

Original Papers, Volume 28, October, Issue 3

KEYWORDS: blood coagulation tests; haemolysis; preanalytical phase

https://doi.org/10.11613/BM.2018.030711

Calcium-stimulated calcitonin - The “new standard” in the diagnosis of thyroid C-cell disease - clinically relevant gender-specific cut-off levels for an “old test”

Martin B. Niederle, Christian Scheuba, Alois Gessl, Shuren Li, Oskar Koperek, Christian Bieglmayer, Philipp Riss, Andreas Selberherr, Bruno Niederle

Original Papers, Volume 28, October, Issue 3

KEYWORDS: medullary thyroid cancer; thyroid; calcitonin; calcium gluconate; pentagastrin

https://doi.org/10.11613/BM.2018.030710

Reducing test request for anti-thyroglobulin and anti-thyroid peroxidase antibodies: trends before and after interventions based on rejection rules and profile management

Pedro Sánchez Pellicer, Ruth González Tamayo, Vicente Navarro López

Original Papers, Volume 28, October, Issue 3

KEYWORDS: demand management laboratory; test laboratory request; anti-thyroid antibodies; anti-thyroid peroxidase antibodies; anti-thyroglobulin antibodies

https://doi.org/10.11613/BM.2018.030709

Evaluation of the analytical performances of the Cobas c513 analyser for HbA1c assay

Stéphane Jaisson, Nathalie Leroy, Michel Soulard, Aurore Desmons, Emmanuelle Guillard, Philippe Gillery

Original Papers, Volume 28, October, Issue 3

KEYWORDS: diabetes; evaluation; HbA; immunoassay

https://doi.org/10.11613/BM.2018.030708

Analysis of selected T cell subsets in peripheral blood after exhaustive effort among elite soccer players

Dorota Kostrzewa-Nowak, Robert Nowak

Original Papers, Volume 28, October, Issue 3

KEYWORDS: athletes; fatigue; flow cytometry; soccer; T-lymphocytes

https://doi.org/10.11613/BM.2018.030707

Computer physician order entry (CPOE) as a strategy to estimate laboratory activity and costs associated with cancer clinical trials

Enrique Rodriguez-Borja, Africa Corchon-Peyrallo, Macarena Diaz-Gimenez, Arturo Carratala-Calvo

Original Papers, Volume 28, October, Issue 3

KEYWORDS: clinical decision support systems; computer physician order entry; health care costs; laboratory management; randomized controlled trials

https://doi.org/10.11613/BM.2018.030706

Effect of sample processing and time delay on cell count and chemistry tests in cerebrospinal fluid collected from drainage systems

Ana Mlinarić, Željka Vogrinc, Zrinka Drenšek

Original Papers, Volume 28, October, Issue 3

KEYWORDS: cerebrospinal fluid; extra-ventricular drainage system; cell count; biochemistry analyses; turnaround time

https://doi.org/10.11613/BM.2018.030705

Haematology specimen acceptability: a national survey in Chinese laboratories

Yuanyuan Ye, Wei Wang, Haijian Zhao, Falin He, Kun Zhong, Shuai Yuan, Yuxuan Du, Bingquan Chen, Zhiguo Wang

Original Papers, Volume 28, October, Issue 3

KEYWORDS: quality indicator; preanalytical phase; quality control; haematology; survey

https://doi.org/10.11613/BM.2018.030704

Detection of annexin A8 antibodies in serum of patients with antiphospholipid syndrome

Philipp Scholz, Markus Auler, Johannes Ruthard, Bent Brachvogel, Andreas R. Klatt, Thomas Streichert

Original Papers, Volume 28, October, Issue 3

KEYWORDS: annexin A8; antiphospholipid syndrome; antiphospholipid antibodies

https://doi.org/10.11613/BM.2018.030703

Association of abdominal aortic aneurysm diameter with insulin resistance index

Fabien Lareyre, Claudine Moratal, Elamine Zereg, Joseph Carboni, Patricia Panaïa-Ferrari, Pascale Bayer, Elixène Jean-Baptiste, Réda Hassen-Khodja, Giulia Chinetti, Juliette Raffort

Original Papers, Volume 28, October, Issue 3

KEYWORDS: diabetes mellitus; abdominal aortic aneurysm; C-peptide; insulin resistance; fructosamine

https://doi.org/10.11613/BM.2018.030702

Improvement of neutrophil gelatinase-associated lipocalin sensitivity and specificity by two plasma measurements in predicting acute kidney injury after cardiac surgery

Giovanni Introcaso, Matteo Nafi, Alice Bonomi, Camilla L’Acqua, Luca Salvi, Roberto Ceriani, Davide Carcione, Annalisa Cattaneo, Maria Teresa Sandri

Original Papers, Volume 28, October, Issue 3

KEYWORDS: neutrophil gelatinase-associated lipocalin; acute kidney injury; cardiovascular surgery; diagnostic accuracy; AKI biomarkers

https://doi.org/10.11613/BM.2018.030701

Red blood cell distribution width in pregnancy: a systematic review

Panagiotis Paliogiannis, Angelo Zinellu, Arduino A. Mangoni, Giampiero Capobianco, Salvatore Dessole, Pier Luigi Cherchi, Ciriaco Carru

Review, Volume 28, October, Issue 3

KEYWORDS: anisocytosis; RDW; pregnancy; preeclampsia; gestational diabetes

https://doi.org/10.11613/BM.2018.030502

“Ultra-sensitive” cardiac troponins: Requirements for effective implementation in clinical practice

Giuseppe Lippi, Fabian Sanchis-Gomar

Review, Volume 28, October, Issue 3

KEYWORDS: cardiac troponin; myocardial infarction; acute coronary syndrome; diagnostics

https://doi.org/10.11613/BM.2018.030501

Informed consent and ethics committee approval in laboratory medicine

Ana Borovecki, Ana Mlinaric, Martina Horvat, Vesna Supak Smolcic

Research Integrity Corner, Volume 28, October, Issue 3

KEYWORDS: informed consent; ethical approval; research; laboratory medicine; ethics committees

https://doi.org/10.11613/BM.2018.030201

Corrigendum to: The potential of component-resolved diagnosis in laboratory diagnostics of allergy

Slavica Dodig, Ivana Čepelak

Corrigendum, Volume 28, June, Issue 2

https://doi.org/10.11613/BM.2018.021201

Evaluating analytical quality in clinical biochemistry laboratory using Six Sigma

Xuehui Mao, Jing Shao, Bingchang Zhang, Yong Wang

Short Communications: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: Sigma metrics; total allowable error; quality control; bias

https://doi.org/10.11613/BM.2018.020904

Using Sigma metrics to establish analytical product performance requirements and optimize analytical performance of an diagnostic assay using a theoretical total PSA assay as an example

Victoria Petrides, Sharon Schneider

Short Communications: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: total quality management; decision making; goals

https://doi.org/10.11613/BM.2018.020903

Comparison of Barricor™ vs. lithium heparin tubes for selected routine biochemical analytes and evaluation of post centrifugation stability

Anne Marie Dupuy, Stéphanie Badiou, Delphine Daubin, Anne Sophie Bargnoux, Chloé Magnan, Kadda Klouche, Jean Paul Cristol

Short Communications, Volume 28, June, Issue 2

KEYWORDS: blood specimen collection; plasma; test tube; evaluation

https://doi.org/10.11613/BM.2018.020902

Storage stability of commonly used haematological parameters at 33 °C

Ashish Jain, Sanchit Jain, Neha Singh, Priyanka Aswal, Shweta Pal, Sushant Kumar Meinia, Nilotpal Chowdhury

Short Communications, Volume 28, June, Issue 2

KEYWORDS: pre-analytical error; erythrocyte indices; laboratory errors; platelet count; sample stability

https://doi.org/10.11613/BM.2018.020901

Utilization of a healthcare failure mode and effects analysis to identify error sources in the preanalytical phase in two tertiary hospital laboratories

Adolfo Romero, Juan Gómez-Salgado, Adolfo Romero-Arana, Carlos Ruiz-Frutos

Original Papers, Volume 28, June, Issue 2

KEYWORDS: preanalytical phase; Healthcare Failure Mode and Effects Analysis; quality assessment; errors

https://doi.org/10.11613/BM.2018.020713

Evaluation of the analytical performances of Cobas 6500 and Sysmex UN series automated urinalysis systems with manual microscopic particle counting

Ebubekir Bakan, Zafer Bayraktutan, Nurcan Kilic Baygutalp, Mehmet Ali Gul, Fatma Zuhal Umudum, Nuri Bakan

Original Papers, Volume 28, June, Issue 2

KEYWORDS: urinalysis; automated urinalysis; manual microscopy

https://doi.org/10.11613/BM.2018.020712

Comparison between Sigma metrics in four accredited Egyptian medical laboratories in some biochemical tests: an initiative towards sigma calculation harmonization

Rania El Sharkawy, Sten Westgard, Ahmed M Awad, AbdelKarem Omneya I Ahmed, El Hadidi Iman, Ahmed Gaballah, Eman Shaheen

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: sigma; bias; coefficient of variation; harmonization; total allowable error

https://doi.org/10.11613/BM.2018.020711

Comprehensive evaluation of the internal and external quality control to redefine analytical quality goals

Beatriz Varela, Gonzalo Pacheco

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: total quality management; quality control; bias; laboratory proficiency testing/methods; clinical chemistry test

https://doi.org/10.11613/BM.2018.020710

Application of Sigma metrics in assessing the clinical performance of verified versus non-verified reagents for routine biochemical analytes

Shuang Cao, Xiaosong Qin

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: quality assessment; Sigma metrics; method decision chart; total allowable error

https://doi.org/10.11613/BM.2018.020709

Sigma metrics for assessing the analytical quality of clinical chemistry assays: a comparison of two approaches

Xiuzhi Guo, Tianjiao Zhang, Xuehui Gao, Pengchang Li, Tingting You, Qiong Wu, Jie Wu, Fang Zhao, Liangyu Xia, Ermu Xu, Ling Qiu, Xinqi Cheng

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: Six Sigma; proficiency testing; internal quality control; allowable total error

https://doi.org/10.11613/BM.2018.020708

Risk analysis and assessment based on Sigma metrics and intended use

Yong Xia, Hao Xue, Cunliang Yan, Bowen Li, ShuQiong Zhang, Mingyang Li, Ling Ji

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: risk analysis; risk assessment; Six Sigma; Sigma metrics; failure mode and effects analysis

https://doi.org/10.11613/BM.2018.020707

Assessing performance in pre-season wrestling athletes using biomarkers

Ionas Papassotiriou, Artemissia-Phoebe Nifli

Original Papers, Volume 28, June, Issue 2

KEYWORDS: exercise; glucose; lactic acid; creatinine; body composition

https://doi.org/10.11613/BM.2018.020706

Verification of a novel point-of-care HbA device in real world clinical practice by comparison to three high performance liquid chromatography instruments

Yufei Wang, Wei Peng, Junling Tang, Lu Dong, Chengchen Gu, Xin Zhang, Jian Zhou, Weiping Jia

Original Papers, Volume 28, June, Issue 2

KEYWORDS: point-of-care testing; glycated haemoglobin A1c; diabetes mellitus; evaluation studies

https://doi.org/10.11613/BM.2018.020705

The impact of delayed sample handling and type of anticoagulant on the interpretation of dysplastic signs detected by flow cytometry

Bettina Kárai, Zsófia Miltényi, Lajos Gergely, Marianna Száraz-Széles, János Kappelmayer, Zsuzsanna Hevessy

Original Papers, Volume 28, June, Issue 2

KEYWORDS: myelodysplastic syndromes; flow cytometry; pre-analytical error

https://doi.org/10.11613/BM.2018.020704

Maturity onset diabetes of the young due to variants in Croatia

Tamara Pavić, Agata Juszczak, Edita Pape Medvidović, Carla Burrows, Mario Šekerija, Amanda J Bennett, Jadranka Ćuća Knežević, Anna L Gloyn, Gordan Lauc, Mark I McCarthy, Olga Gornik, Katharine R Owen

Original Papers, Volume 28, June, Issue 2

KEYWORDS: ; maturity onset diabetes of the young (MODY); monogenic diabetes; prevalence study

https://doi.org/10.11613/BM.2018.020703

National survey on internal quality control for tumour markers in clinical laboratories in China

Wei Wang, Kun Zhong, Shuai Yuan, Falin He, Yuxuan Du, Zhehui Hu, Zhiguo Wang

Original Papers, Volume 28, June, Issue 2

KEYWORDS: internal quality control; tumour marker; imprecision; biological variation

https://doi.org/10.11613/BM.2018.020702

Effect of different pre-analytical conditions on plasma lactate concentration

Ivana Rako, Ana Mlinaric, Monika Dozelencic, Gordana Fressl Juros, Dunja Rogic

Original Papers, Volume 28, June, Issue 2

KEYWORDS: plasma lactate; blood analysis; blood specimen collection; haemolysis; pre-analytical phase

https://doi.org/10.11613/BM.2018.020701

Sigma metrics in laboratory medicine revisited: We are on the right road with the wrong map

Wytze P. Oosterhuis, Abdurrahman Coskun

Review: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: biological variation; Six Sigma; Sigma metrics; total error; number of distinct categories

https://doi.org/10.11613/BM.2018.020503

Analytical Sigma metrics: A review of Six Sigma implementation tools for medical laboratories

Sten Westgard, Hassan Bayat, James O Westgard

Review: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: Six Sigma metrics; quality control frequency; OPSpecs chart; method decision chart; Westgard rules

https://doi.org/10.11613/BM.2018.020502

The potential of component-resolved diagnosis in laboratory diagnostics of allergy

Slavica Dodig, Ivana Čepelak

Review, Volume 28, June, Issue 2

KEYWORDS: allergy; IgE; component-resolved diagnosis

https://doi.org/10.11613/BM.2018.020501

Special issue on Six Sigma metrics - experiences and recommendations

Sten Westgard, Hassan Bayat, James O Westgard

Editorial: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: Six Sigma; Sigma metrics; quality control

https://doi.org/10.11613/BM.2018.020301

Expected long-term defect rate of analytical performance in the medical laboratory: Assured Sigma versus observed Sigma

Hassan Bayat

Lessons in Biostatistics: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: medical laboratory; Sigma metrics; Six Sigma; allowable total error

https://doi.org/10.11613/BM.2018.020101

Corrigendum to: Nurses’ knowledge on phlebotomy in tertiary hospitals in China: a cross-sectional multicentric survey

Qian Cai, Yunxian Zhou, Dagan Yang

Corrigendum, Volume 28, February, Issue 1

https://doi.org/10.11613/BM.2018.011202

Corrigendum to: Minimum requirements for the estimation of the measurement uncertainty: Recommendations of the joint Working group for uncertainty of measurement of the CSMBLM and CCMB

Ivana Ćelap, Ines Vukasović, Gordana Juričić, Ana-Maria Šimundić

Corrigendum, Volume 28, February, Issue 1

https://doi.org/10.11613/BM.2018.011201

Pseudohyperkalemia - Potassium released from cells due to clotting and centrifugation - a case report

Tomáš Šálek

Pre-analytical Mysteries, Volume 28, February, Issue 1

KEYWORDS: hyperkalemia; case report; electrolytes; pseudohyperkalemia

https://doi.org/10.11613/BM.2018.011002

Elevated zinc concentrations in a 5 months old infant: A case report

Eva Rabing Brix Petersen, Sven Mortensen, Mads Nybo

Pre-analytical Mysteries, Volume 28, February, Issue 1

KEYWORDS: capillary blood sample; case report; pre-analytical phase; zinc

https://doi.org/10.11613/BM.2018.011001

Neutrophil gelatinase-associated lipocalin and acute kidney injury in endovascular aneurysm repair or open aortic repair: a pilot study

Benedetta Rampoldi, Serena Tessarolo, Paola Giubbilini, Paola Gaia, Samantha D. Corino, Sarah Mazza, Roberta Rigolini, Marco Dei Poli, Elena Vianello, Massimiliano M. Corsi Romanelli, Elena Costa

Short Communications, Volume 28, February, Issue 1

KEYWORDS: acute kidney injury; neutrophil gelatinase-associated lipocalin; cardiovascular surgery; early detection; urinary biomarkers

https://doi.org/10.11613/BM.2018.010904

Upfront dilution of ferritin samples to reduce hook effect, improve turnaround time and reduce costs

Shu Juan Wu, Joshua A. Hayden

Short Communications, Volume 28, February, Issue 1

KEYWORDS: immunoassay; prozone effect; ferritin; turnaround time

https://doi.org/10.11613/BM.2018.010903

Reference intervals for six salivary cortisol measures based on the Croatian Late Adolescence Stress Study (CLASS)

Daniela Šupe-Domić, Goran Milas, Lada Stanišić, Irena Drmić Hofman, Irena Martinović Klarić

Short Communications, Volume 28, February, Issue 1

KEYWORDS: salivary cortisol; reference intervals; late adolescence

https://doi.org/10.11613/BM.2018.010902

Appropriateness of digoxin measurement in hospitalized patients

Seyma Oncu, Ayse Gelal, Ozgur Aslan, Reyhan S Ucku

Short Communications, Volume 28, February, Issue 1

KEYWORDS: digoxin; therapeutic drug monitoring; heart failure; electronic health records

https://doi.org/10.11613/BM.2018.010901

Gamma heavy-chain disease accompanied with follicular lymphoma: a case report

Paula San-José, Vicente Aguadero, Granada Perea, Meritxell Estrada, Eugenio Berlanga

Case Reports, Volume 28, February, Issue 1

KEYWORDS: paraproteins; electrophoresis; lymphoma; heavy chain disease

https://doi.org/10.11613/BM.2018.010802

Henoch-Schönlein purpura in the third trimester of pregnancy

Ivka Djakovic, Drazan Butorac, Zeljko Vucicevic, Vesna Kosec, Andrea Tesija Kuna, Liborija Lugović-Mihić

Case Reports, Volume 28, February, Issue 1

KEYWORDS: Henoch-Schönlein purpura; leukocytoclastic vasculitis; pregnancy; glomerulonephritis; preeclampsia

https://doi.org/10.11613/BM.2018.010801

Reference interval for immature platelet fraction on Sysmex XN haematology analyser in adult population

Claudia E. Imperiali, Ariadna Arbiol-Roca, Lourdes Sanchez-Navarro, Macarena Dastis-Arias, Juan C. Lopez-Delgado, Anna Cortes-Bosch, Ana Sancho-Cerro, Dolors Dot-Bach

Original Papers, Volume 28, February, Issue 1

KEYWORDS: platelets; haematology; reference values; immature platelet fraction

https://doi.org/10.11613/BM.2018.010708

Preanalytics of urine sediment examination: effect of relative centrifugal force, tube type, volume of sample and supernatant removal

Amalija Bunjevac, Nora Nikolac Gabaj, Marijana Miler, Anita Horvat

Original Papers, Volume 28, February, Issue 1

KEYWORDS: preanalytical phase; laboratory error; urinalysis; urine sediment

https://doi.org/10.11613/BM.2018.010707

Diagnostic value of tumour markers in pleural effusions

Darian Volarić, Veljko Flego, Gordana Žauhar, Ljiljana Bulat-Kardum

Original Papers, Volume 28, February, Issue 1

KEYWORDS: pleural effusion; CA-125 antigen; carcinoembryonic antigen; neuron-specific enolase; cytokeratin 19 fragment

https://doi.org/10.11613/BM.2018.010706

Missed detection of significant positive and negative shifts in gentamicin assay: implications for routine laboratory quality practices

Gus Koerbin, Jiakai Liu, Alex Eigenstetter, Chin Hon Tan, Tony Badrick, Tze Ping Loh

Original Papers, Volume 28, February, Issue 1

KEYWORDS: error; moving average; bias; quality control; quality assurance

https://doi.org/10.11613/BM.2018.010705

Influence of centrifugation conditions on the results of 77 routine clinical chemistry analytes using standard vacuum blood collection tubes and the new BD-Barricor tubes

Janne Cadamuro, Cornelia Mrazek, Alexander B. Leichtle, Ulrike Kipman, Thomas K. Felder, Helmut Wiedemann, Hannes Oberkofler, Georg M. Fiedler, Elisabeth Haschke-Becher

Original Papers, Volume 28, February, Issue 1

KEYWORDS: pre-analytics; centrifugation; diagnostic tests; routine

https://doi.org/10.11613/BM.2018.010704

Nurses’ knowledge on phlebotomy in tertiary hospitals in China: a cross-sectional multicentric survey

Qian Cai, Yunxian Zhou, Dangan Yang

Original Papers, Volume 28, February, Issue 1

KEYWORDS: pre-analytical phase; venous blood sampling; knowledge; nurses; phlebotomy

https://doi.org/10.11613/BM.2018.010703

Fasting conditions: Influence of water intake on clinical chemistry analytes

Silvia F. Benozzi, Gisela Unger, Amparo Campion, Graciela L. Pennacchiotti

Original Papers, Volume 28, February, Issue 1

KEYWORDS: fasting; water intake; blood sample collection; preanalytical variability; clinical chemistry tests

https://doi.org/10.11613/BM.2018.010702

Reliability of CKD-EPI predictive equation in estimating chronic kidney disease prevalence in the Croatian endemic nephropathy area

Mirjana Fuček, Živka Dika, Sandra Karanović, Ivana Vuković Brinar, Vedran Premužić, Jelena Kos, Ante Cvitković, Maja Mišić, Josip Samardžić, Dunja Rogić, Bojan Jelaković

Original Papers, Volume 28, February, Issue 1

KEYWORDS: chronic kidney disease; estimated glomerular filtration rate; predictive equation; endemic nephropathy

https://doi.org/10.11613/BM.2018.010701

Biochemia Medica appoints new Editor-in-Chief and new Senior Editor

Daria Pašalić

Editorial, Volume 28, February, Issue 1

KEYWORDS: editor; journal; scientific writing; publication

https://doi.org/10.11613/BM.2018.010301

Setting the IMPACT (IMProve Access to Clinical Trial data) Observatory baseline

Mersiha Mahmić-Kaknjo, Josip Šimić, Karmela Krleža-Jerić

Research Integrity Corner, Volume 28, February, Issue 1

KEYWORDS: clinical trial data sharing; baseline; databases; registries; Cochrane; scandals

https://doi.org/10.11613/BM.2018.010201

Bayes’ theorem, the ROC diagram and reference values: Definition and use in clinical diagnosis

Anders Kallner

Lessons in Biostatistics, Volume 28, February, Issue 1

KEYWORDS: likelihood ratio; cumulative data analysis; odds; sensitivity; specificity

https://doi.org/10.11613/BM.2018.010101

External quality assessment in resource–limited countries

Jane Y Carter

Special Issue: External Quality Assessment in Laboratory Medicine - Original Papers, Volume 27, February, Issue 1

KEYWORDS: laboratory; quality assurance; proficiency testing; resource-limited countries

https://doi.org/10.11613/BM.2017.013

Implementation of the External Quality Assessment Program in Brazil

Marcos Kneip Fleury, Maria Elizabeth Menezes, José Abol Correa

Special Issue: External Quality Assessment in Laboratory Medicine - Review, Volume 27, February, Issue 1

KEYWORDS: quality assurance; external assessment; proficiency testing

https://doi.org/10.11613/BM.2017.012

External Quality Assessment in Croatia: problems, challenges, and specific circumstances

Jasna Lenicek Krleza, Ivana Celap, Jelena Vlasic Tanaskovic

Special Issue: External Quality Assessment in Laboratory Medicine - Review, Volume 27, February, Issue 1

KEYWORDS: external quality assessment; commutability; allowable limit of performance; standardization; harmonization

https://doi.org/10.11613/BM.2017.011